Effects of gastrodin against carbon tetrachloride induced kidney inflammation and fibrosis in mice associated with the AMPK/Nrf2/HMGB1 pathway.

AMP-Activated Protein Kinase Kinases Animals Benzyl Alcohols / administration & dosage Carbon Tetrachloride Disease Models, Animal Fibrosis / prevention & control Glucosides / administration & dosage HMGB1 Protein / metabolism Inflammation / prevention & control Kidney Diseases / prevention & control Male Mice Mice, Inbred ICR NF-E2-Related Factor 2 / metabolism Phytotherapy Protein Kinases / metabolism

Journal

Food & function
ISSN: 2042-650X
Titre abrégé: Food Funct
Pays: England
ID NLM: 101549033

Informations de publication

Date de publication:
01 May 2020
Historique:
pubmed: 14 5 2020
medline: 19 3 2021
entrez: 14 5 2020
Statut: ppublish

Résumé

Gastrodin (GAS), the main phenolic glycoside extracted from Gastrodia elata Blume, exhibits potential renoprotective properties. Here, we examined the protective effects of GAS on carbon tetrachloride (CCl

Identifiants

DOI: 10.1039/d0fo00711k PMID: 32400831
pubmed: 32400831
doi: 10.1039/d0fo00711k
doi:

Substances chimiques

Benzyl Alcohols 0
Glucosides 0
HMGB1 Protein 0
NF-E2-Related Factor 2 0
gastrodin 5YS9U2W3RQ
Carbon Tetrachloride CL2T97X0V0
Protein Kinases EC 2.7.-
AMP-Activated Protein Kinase Kinases EC 2.7.11.3

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

4615-4624

Auteurs

Jie-Qiong Ma (JQ)

School of Chemistry Engineering, Sichuan University of Science and Engineering, No. 180, Huixing Road, 643000, Zigong City, Sichuan Province, PR China. a1032042419@126.com.

Yun-Zhi Sun (YZ)

Qing-Lei Ming (QL)

Zhi-Kai Tian (ZK)

Yu-Jia Zhang (YJ)

Chan-Min Liu (CM)

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protein-Serine-Threonine Kinases › AMP-activated protein kinase kinases › Effects of gastrodin against carbon...
questionsmedicales.fr › Eucaryotes › Animaux › Effects of gastrodin against carbon...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Composés benzyliques › Alcools benzyliques › Effects of gastrodin against carbon...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures halogénés › Hydrocarbures chlorés › Tétrachloro-méthane › Effects of gastrodin against carbon...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Effects of gastrodin against carbon...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Fibrose › Effects of gastrodin against carbon...
questionsmedicales.fr › Glucides › Hétérosides › Glucosides › Effects of gastrodin against carbon...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Nucléoprotéines › Protéines chromosomiques nonhistones › Protéines HMG › Protéines HMGB › Protéine HMGB1 › Effects of gastrodin against carbon...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Effects of gastrodin against carbon...
questionsmedicales.fr › Maladies urogénitales › Maladies urologiques › Maladies du rein › Effects of gastrodin against carbon...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Effects of gastrodin against carbon...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée ICR › Effects of gastrodin against carbon...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription à motif basique et à glissière à leucines › Facteur-2 apparenté à NF-E2 › Effects of gastrodin against carbon...
questionsmedicales.fr › Thérapeutique › Thérapies complémentaires › Phytothérapie › Effects of gastrodin against carbon...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Transferases › Phosphotransferases › Phosphotransferases (Alcohol Group Acceptor) › Protein kinases › Effects of gastrodin against carbon...