Perioperative outcomes of robot-assisted vs video-assisted and traditional open thoracic surgery for lung cancer: A systematic review and network meta-analysis.
lung cancer
meta-analysis
robotic surgery
thoracoscopic surgery
thoracotomy
Journal
The international journal of medical robotics + computer assisted surgery : MRCAS
ISSN: 1478-596X
Titre abrégé: Int J Med Robot
Pays: England
ID NLM: 101250764
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
10
12
2019
revised:
06
05
2020
accepted:
08
05
2020
pubmed:
14
5
2020
medline:
19
8
2021
entrez:
14
5
2020
Statut:
ppublish
Résumé
The superiority of robot-assisted thoracic surgery (RATS) over video-assisted thoracic surgery (VATS) and thoracotomy remains controversial for lung cancer. A network meta-analysis (NMA) and pairwise meta-analysis (PMA) were performed to evaluate the perioperative outcomes using five databases. Thirty-two studies involving 6593 patients were included for analysis. The NMA showed that RATS had similar operative time, conversion rate to thoracotomy, number of lymph node, postoperative morbidity, and length of hospital stay with VATS, except for lower 30-day mortality. Compared with thoracotomy, longer operative time and shorter hospital stay were observed in RATS, but no significant difference was observed in number of lymph node, postoperative morbidity, and 30-day mortality in both NMA and PMA. In lobectomy/segmentectomy subgroup, all outcomes, except for operative time of RATS vs VATS and number of lymph node, were similar with overall analyses. RATS had comparable perioperative outcomes with VATS and open surgery.
Sections du résumé
BACKGROUND
BACKGROUND
The superiority of robot-assisted thoracic surgery (RATS) over video-assisted thoracic surgery (VATS) and thoracotomy remains controversial for lung cancer.
METHODS
METHODS
A network meta-analysis (NMA) and pairwise meta-analysis (PMA) were performed to evaluate the perioperative outcomes using five databases.
RESULTS
RESULTS
Thirty-two studies involving 6593 patients were included for analysis. The NMA showed that RATS had similar operative time, conversion rate to thoracotomy, number of lymph node, postoperative morbidity, and length of hospital stay with VATS, except for lower 30-day mortality. Compared with thoracotomy, longer operative time and shorter hospital stay were observed in RATS, but no significant difference was observed in number of lymph node, postoperative morbidity, and 30-day mortality in both NMA and PMA. In lobectomy/segmentectomy subgroup, all outcomes, except for operative time of RATS vs VATS and number of lymph node, were similar with overall analyses.
CONCLUSIONS
CONCLUSIONS
RATS had comparable perioperative outcomes with VATS and open surgery.
Types de publication
Journal Article
Meta-Analysis
Review
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1-14Subventions
Organisme : Fundamental Research Funds for the Central Universities
ID : 22120180510
Organisme : National Natural Science Foundation of China
ID : 81972172
Organisme : Shanghai Education Development Foundation
ID : 17SG23
Organisme : Shanghai Municipal Health Commission
ID : 2017BR026
Organisme : Shanghai Municipal Human Resources and Social Securitiy Bureau
ID : 2017114
Informations de copyright
© 2020 John Wiley & Sons Ltd.
Références
Bendixen M, Jørgensen OD, Kronborg C, Andersen C, Licht PB. Postoperative pain and quality of life after lobectomy via video-assisted thoracoscopic surgery or anterolateral thoracotomy for early stage lung cancer: a randomised controlled trial. Lancet Oncol. 2016;17:836-844.
Boffa DJ, Kosinski AS, Furnary AP, et al. Minimally invasive lung cancer surgery performed by thoracic surgeons as effective as thoracotomy. J Clin Oncol. 2018;36:2378-2385.
Yan TD, Black D, Bannon PG, McCaughan BC. Systematic review and meta-analysis of randomized and nonrandomized trials on safety and efficacy of video-assisted thoracic surgery lobectomy for early-stage non-small-cell lung cancer. J Clin Oncol. 2009;27:2553-2562.
Boffa DJ, Allen MS, Grab JD, Gaissert HA, Harpole DH, Wright CD. Data from the Society of Thoracic Surgeons general thoracic surgery database: the surgical management of primary lung tumors. J Thorac Cardiovasc Surg. 2008;135:247-254.
Rocco G, Internullo E, Cassivi SD, van Raemdonck D, Ferguson MK. The variability of practice in minimally invasive thoracic surgery for pulmonary resections. Thorac Surg Clin. 2008;18:235-247.
Melfi FM, Menconi GF, Mariani AM, Angeletti CA. Early experience with robotic technology for thoracoscopic surgery. Eur J Cardiothorac Surg. 2002;21:864-868.
Oh DS, Reddy RM, Gorrepati ML, Mehendale S, Reed MF. Robotic-assisted, video-assisted Thoracoscopic and open lobectomy: propensity-matched analysis of recent premier data. Ann Thorac Surg. 2017;104:1733-1740.
Novellis P, Bottoni E, Voulaz E, et al. Robotic surgery, video-assisted thoracic surgery, and open surgery for early stage lung cancer: comparison of costs and outcomes at a single institute. J Thorac Dis. 2018;10:790-798.
Liang H, Liang W, Zhao L, et al. Robotic versus video-assisted lobectomy/Segmentectomy for lung cancer: a meta-analysis. Ann Surg. 2018;268:254-259.
Wei S, Chen M, Chen N, Liu L. Feasibility and safety of robot-assisted thoracic surgery for lung lobectomy in patients with non-small cell lung cancer: a systematic review and meta-analysis. World J Surg Oncol. 2017;15:98.
O'Sullivan KE, Kreaden US, Hebert AE, Eaton D, Redmond KC. A systematic review and meta-analysis of robotic versus open and video-assisted thoracoscopic surgery approaches for lobectomy. Interact Cardiovasc Thorac Surg. 2019;28:526-534.
Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol. 2009;62:1006-1012.
Stroup DF, Berlin JA, Morton SC, et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis of observational studies in epidemiology (MOOSE) group. JAMA. 2000;283:2008-2012.
Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol. 2010;25:603-605.
Salanti G, Higgins JPT, Ades AE, Ioannidis JPA. Evaluation of networks of randomized trials. Stat Methods Med Res. 2008;17:279-301.
Brooks SP, Gelman A. General methods for monitoring convergence of iterative simulations. J Comput Graph Stat. 1998;7:434-455.
Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ (Clinical Res Ed). 2003;327:557-560.
DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7:177-188.
Wan X, Wang W, Liu J, Tong T. Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range. BMC Med Res Methodol. 2014;14:135.
Seagroatt V, Stratton I. Bias in meta-analysis detected by a simple, graphical test. Test had 10% false positive rate. BMJ (Clinical Res Ed). 1998;316:470.
Xie B, Sun X, Qin Y, Liu A, Miao S, Jiao W. Short-term outcomes of typical versus atypical lung segmentectomy by minimally invasive surgeries. Thoracic Cancer. 2019;10:1812-1818.
van der Ploeg APT, Ayez N, Akkersdijk GP, et al. Postoperative pain after lobectomy: robot-assisted, video-assisted and open thoracic surgery. J Robot Surg. 2020;14(1):131-136.
Qiu T, Zhao Y, Xuan Y, et al. Robotic sleeve lobectomy for centrally located non-small cell lung cancer: a propensity score-weighted comparison with thoracoscopic and open surgery. J Thoracic Cardiovascular Surg. 2019; In press.
Nguyen DT, Meisenbach LM, Graviss EA, et al. Da Vinci xi robot decreases the number of thoracotomy cases in pulmonary resection. J Thorac Dis. 2019;11:145-153.
Nelson DB, Mehran RJ, Mitchell KG, et al. Robotic assisted lobectomy for non-small cell lung cancer: a comprehensive institutional experience. Ann Thorac Surg. 2019;108(2):370-376.
Li J-T, Liu P-Y, Hung J, et al. Perioperative outcomes of radical lobectomies using robotic-assisted thoracoscopic technique vs. video-assisted thoracoscopic technique: retrospective study of 1,075 consecutive p-stage I non-small cell lung cancer cases. J Thorac Dis. 2019;11:882-891.
Kneuertz PJ, D'Souza DM, Richardson M, et al. Long-term oncologic outcomes after robotic lobectomy for early-stage non-small-cell lung cancer versus video-assisted thoracoscopic and open thoracotomy approach. Clin Lung Cancer. 2020;21(3):214.e2-224.e2.
Huang L, Shen Y, Onaitis M. Comparative study of anatomic lung resection by robotic vs. video-assisted thoracoscopic surgery. J Thorac Dis. 2019;11:1243-1250.
Casiraghi M, Sedda G, Diotti C, et al. Postoperative outcomes of robotic-assisted lobectomy in obese patients with non-small-cell lung cancer. Interact Cardiovasc Thorac Surg. 2020;30(3):359-365.
Zirafa C, Aprile V, Ricciardi S, et al. Nodal upstaging evaluation in NSCLC patients treated by robotic lobectomy. Surg Endosc. 2019;33(1):153-158.
Yang S, Guo W, Chen X, Wu H, Li H. Early outcomes of robotic versus uniportal video-assisted thoracic surgery for lung cancer: a propensity score-matched study. Eur J Cardiothorac Surg. 2018;53:348-352.
Worrell SG, Dedhia P, Gilbert C, et al. The cost and quality of life outcomes in developing a robotic lobectomy program. J Robot Surg. 2019;13(2):239-243.
Kaur NM, Xie F, Shiwcharan A, et al. Robotic versus video-assisted thoracoscopic lung resection during early program development. Ann Thorac Surg. 2018;105:1050-1057.
Gu C, Pan X, Chen Y, Yang J, Zhao H, Shi J. Short-term and mid-term survival in bronchial sleeve resection by robotic system versus thoracotomy for centrally located lung cancer. Eur J Cardiothorac Surg. 2018;53:648-655.
Yang H-X, Woo KM, Sima CS, et al. Long-term survival based on the surgical approach to lobectomy for clinical stage I nonsmall cell lung cancer comparison of robotic, video-assisted thoracic surgery, and thoracotomy lobectomy. Ann Surg. 2017;265:431-437.
Park SY, Suh JW, Narm KS, et al. Feasibility of four-arm robotic lobectomy as solo surgery in patients with clinical stage I lung cancer. J Thorac Dis. 2017;9:1607-1614.
Kwon ST, Zhao L, Reddy RM, et al. Evaluation of acute and chronic pain outcomes after robotic, video-assisted thoracoscopic surgery, or open anatomic pulmonary resection. J Thorac Cardiovasc Surg. 2017;154:652-659.e651.
Rinieri P, Peillon C, Salaün M, Mahieu J, Bubenheim M, Baste JM. Perioperative outcomes of video- and robot-assisted segmentectomies. Asian Cardiovascular Thoracic Ann. 2016;24:145-151.
Mungo B, Hooker CM, Ho JSY, et al. Robotic versus thoracoscopic resection for lung cancer: early results of a new robotic program. J Laparoendoscop Adv Surg Tech. 2016;26:243-248.
Mahieu J, Rinieri P, Bubenheim M, et al. Robot-assisted thoracoscopic surgery versus video-assisted thoracoscopic surgery for lung lobectomy: can a robotic approach improve short-term outcomes and operative safety? Thorac Cardiovasc Surg. 2016;64:354-362.
Bao F, Zhang C, Yang Y, He Z, Wang L, Hu J. Comparison of robotic and video-assisted thoracic surgery for lung cancer: a propensity-matched analysis. J Thorac Dis. 2016;8:1798-1803.
Lee BE, Shapiro M, Rutledge JR, Korst RJ. Nodal upstaging in robotic and video assisted thoracic surgery lobectomy for clinical N0 lung cancer. Ann Thorac Surg. 2015;100:229-233. discussion 233-224.
Demir A, Ayalp K, Ozkan B, Kaba E, Toker A. Robotic and video-assisted thoracic surgery lung segmentectomy for malignant and benign lesions. Interact Cardiovasc Thorac Surg. 2015;20:304-309.
Spillane J, Brooks P. Developing a robotic program in thoracic surgery at Cape Cod hospital. J Robot Surg. 2014;8:213-220.
Deen SA, Wilson JL, Wilshire CL, et al. Defining the cost of care for lobectomy and segmentectomy: a comparison of open, video-assisted thoracoscopic, and robotic approaches. Ann Thorac Surg. 2014;97:1000-1007.
Augustin F, Bodner J, Maier H, et al. Robotic-assisted minimally invasive vs. thoracoscopic lung lobectomy: comparison of perioperative results in a learning curve setting. Langenbecks Arch Surg. 2013;398:895-901.
Jang H-J, Lee H-S, Park SY, et al. Comparison of the early robot-assisted lobectomy experience to video-assisted thoracic surgery lobectomy for lung cancer: a single-institution case series matching study. Innovations (Philadelphia, Pa). 2011;6:305-310.
Cerfolio RJ, Bryant AS, Skylizard L, Minnich DJ. Initial consecutive experience of completely portal robotic pulmonary resection with 4 arms. J Thorac Cardiovasc Surg. 2011;142:740-746.
Veronesi G, Galetta D, Maisonneuve P, et al. Four-arm robotic lobectomy for the treatment of early-stage lung cancer. J Thorac Cardiovasc Surg. 2010;140:19-25.
Zhang Y, Chen C, Hu J, et al. Early outcomes of robotic versus thoracoscopic segmentectomy for early-stage lung cancer: a multi-institutional propensity score-matched analysis. J Thorac Cardiovasc Surg. 2020; In press.
Haruki T, Kubouchi Y, Takagi Y, et al. Comparison of medium-term survival outcomes between robot-assisted thoracoscopic surgery and video-assisted thoracoscopic surgery in treating primary lung cancer. Gen Thorac Cardiovasc Surg. 2020; In press.
Yoshino I, Hashizume M, Shimada M, et al. Thoracoscopic thymomectomy with the da Vinci computer-enhanced surgical system. J Thorac Cardiovasc Surg. 2001;122:783-785.
Buentzel J, Heinz J, Hinterthaner M, et al. Robotic versus thoracoscopic thymectomy: the current evidence. Int J Med Robot. 2017;13:e1847.
van Hillegersberg R, Boone J, Draaisma WA, Broeders IAMJ, Giezeman MJMM, Rinkes IHMB. First experience with robot-assisted thoracoscopic esophagolymphadenectomy for esophageal cancer. Surg Endosc. 2006;20:1435-1439.
Yoshino I, Hashizume M, Shimada M, Tomikawa M, Sugimachi K. Video-assisted thoracoscopic extirpation of a posterior mediastinal mass using the da Vinci computer enhanced surgical system. Ann Thorac Surg. 2002;74:1235-1237.
Latif MJ, Afthinos JN, Connery CP, et al. Robotic intercostal nerve graft for reversal of thoracic sympathectomy: a large animal feasibility model. Int J Med Robot. 2008;4:258-262.
Park BJ, Flores RM, Rusch VW. Robotic assistance for video-assisted thoracic surgical lobectomy: technique and initial results. J Thorac Cardiovasc Surg. 2006;131:54-59.
Fortes DL, Tomaszek SC, Wigle DA. Early experience with robotic-assisted lung resection. Innovations (Phila). 2011;6:237-242.
Gharagozloo F, Margolis M, Tempesta B, Strother E, Najam F. Robot-assisted lobectomy for early-stage lung cancer: report of 100 consecutive cases. Ann Thorac Surg. 2009;88:380-384.
Kneuertz PJ, D'Souza DM, Moffatt-Bruce SD, Merritt RE. Robotic lobectomy has the greatest benefit in patients with marginal pulmonary function. J Cardiothorac Surg. 2018;13:56.
Louie BE, Wilson JL, Kim S, et al. Comparison of video-assisted Thoracoscopic surgery and robotic approaches for clinical stage I and stage II non-small cell lung cancer using the Society of Thoracic Surgeons database. Ann Thorac Surg. 2016;102:917-924.
Emmert A, Straube C, Buentzel J, Roever C. Robotic versus thoracoscopic lung resection a systematic review and meta-analysis. Medicine. 2017;96:e7633.
Zhang L, Gao S. Robot-assisted thoracic surgery versus open thoracic surgery for lung cancer: a system review and meta-analysis. Int J Clin Exp Med. 2015;8:17804-17810.
Yang CF, Sun Z, Speicher PJ, et al. Use and outcomes of minimally invasive lobectomy for stage I non-small cell lung cancer in the National Cancer Data Base. Ann Thorac Surg. 2016;101:1037-1042.
Meyer M, Gharagozloo F, Tempesta B, Margolis M, Strother E, Christenson D. The learning curve of robotic lobectomy. Int J Med Robot Comput Assist Surg. 2012;8:448-452.
Arnold BN, Thomas DC, Bhatnagar V, et al. Defining the learning curve in robot-assisted thoracoscopic lobectomy. Surgery. 2019;165:450-454.
Baldonado J, Amaral M, Garrett J, et al. Credentialing for robotic lobectomy: what is the learning curve? A retrospective analysis of 272 consecutive cases by a single surgeon. J Robot Surg. 2019;13(5):663-669.
Taniguchi Y, Nakamura H, Miwa K, et al. Initial results of robotic surgery for primary lung cancer: feasibility, safety and learning curve. Yonago Acta Med. 2017;60:162-166.
White YN, Dedhia P, Bergeron EJ, Lin J, Chang AA, Reddy RM. Resident training in a new robotic thoracic surgery program. J Surg Res. 2016;201:219-225.
Le Gac C, Gondé H, Gillibert A, et al. Medico-economic impact of robot-assisted lung segmentectomy: what is the cost of the learning curve? Interact Cardiovasc Thorac Surg. 2020;30:255-262.
Song G, Sun X, Miao S, et al. Learning curve for robot-assisted lobectomy of lung cancer. J Thorac Dis. 2019;11:2431-2437.
Merritt RE, Kneuertz PJ, D'Souza DM. Successful transition to robotic-assisted lobectomy with previous proficiency in thoracoscopic lobectomy. Innovations (Philadelphia, Pa). 2019;14:263-271.
Cheufou DH, Mardanzai K, Ploenes T, et al. Effectiveness of robotic lobectomy-outcome and learning curve in a high volume center. Thorac Cardiovasc Surg. 2019;67:573-577.
Sato Y, Tezuka Y, Kanai Y, et al. Novel retractor for lymph node dissection by video-assisted thoracic surgery. Ann Thorac Surg. 2008;86:1036-1037.
Toker A, Ozyurtkan MO, Demirhan O, et al. Lymph node dissection in surgery for lung cancer: comparison of open vs. video-assisted vs. robotic-assisted approaches. Ann Thorac Cardiovasc Surg. 2016;22:284-290.
Yu Z, Xie Q, Guo L, et al. Perioperative outcomes of robotic surgery for the treatment of lung cancer compared to a conventional video-assisted thoracoscopic surgery (VATS) technique. Oncotarget. 2017;8:91076-91084.
Kent M, Wang T, Whyte R, Curran T, Flores R, Gangadharan S. Open, video-assisted thoracic surgery, and robotic lobectomy: review of a national database. Ann Thorac Surg. 2014;97:236-242. discussion 242-234.
Farivar AS, Cerfolio RJ, Vallieres E, et al. Comparing robotic lung resection with thoracotomy and video-assisted thoracoscopic surgery cases entered into the Society of Thoracic Surgeons database. Innovations (Phila). 2014;9:10-15.
Adams RD, Bolton WD, Stephenson JE, Henry G, Robbins ET, Sommers E. Initial multicenter community robotic lobectomy experience: comparisons to a national database. Ann Thorac Surg. 2014;97:1893-1900.
Veluswamy RR, Whittaker Brown S-A, Mhango G, et al. Comparative effectiveness of robotic-assisted surgery for resectable lung cancer in older patients. Chest. 2020;157(5):1313-1321.