Aged
Altitude
Antineoplastic Combined Chemotherapy Protocols
/ therapeutic use
Asian People
/ genetics
Carcinoma, Non-Small-Cell Lung
/ diagnosis
Case-Control Studies
China
Cisplatin
/ therapeutic use
Female
Genetic Association Studies
Genetic Predisposition to Disease
Humans
Lung Neoplasms
/ diagnosis
Male
Middle Aged
Phenotype
Polymorphism, Single Nucleotide
Rad52 DNA Repair and Recombination Protein
/ genetics
Risk Assessment
Risk Factors
Treatment Outcome
RAD52
chemotherapy
clinical index
high altitude
non-small cell lung cancer
Journal
Therapeutic advances in respiratory disease
ISSN: 1753-4666
Titre abrégé: Ther Adv Respir Dis
Pays: England
ID NLM: 101316317
Informations de publication
Date de publication:
Historique:
entrez:
14
5
2020
pubmed:
14
5
2020
medline:
2
6
2021
Statut:
ppublish
Résumé
Non-small cell lung cancer (NSCLC) accounts for approximately 80% of diagnosed lung cancer patients. Eight single nucleotide polymorphisms (SNPs) of The rs10774474 A allele was related to a decreased risk of NSCLC in a high altitude population of China (OR = 0.82, 95% CI = 0.69-0.98, Our findings suggested the remarkable association of
Sections du résumé
BACKGROUND
Non-small cell lung cancer (NSCLC) accounts for approximately 80% of diagnosed lung cancer patients.
METHODS
Eight single nucleotide polymorphisms (SNPs) of
RESULTS
The rs10774474 A allele was related to a decreased risk of NSCLC in a high altitude population of China (OR = 0.82, 95% CI = 0.69-0.98,
CONCLUSIONS
Our findings suggested the remarkable association of
Identifiants
pubmed: 32401173
doi: 10.1177/1753466620918192
pmc: PMC7223216
doi:
Substances chimiques
RAD52 protein, human
0
Rad52 DNA Repair and Recombination Protein
0
Cisplatin
Q20Q21Q62J
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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