Dose and cardiopulmonary effects of propofol alone or with midazolam for induction of anesthesia in critically ill dogs.


Journal

Veterinary anaesthesia and analgesia
ISSN: 1467-2995
Titre abrégé: Vet Anaesth Analg
Pays: United States
ID NLM: 100956422

Informations de publication

Date de publication:
Jul 2020
Historique:
received: 03 12 2019
revised: 29 03 2020
accepted: 31 03 2020
pubmed: 14 5 2020
medline: 10 4 2021
entrez: 14 5 2020
Statut: ppublish

Résumé

To determine the dose and cardiopulmonary effects of propofol alone or with midazolam for induction of anesthesia in American Society of Anesthesiologists status ≥III dogs requiring emergency abdominal surgery. Prospective, randomized, blinded, clinical trial. A total of 19 client-owned dogs. Dogs were sedated with fentanyl (2 μg kg There were no differences in group demographics, temperature and cardiopulmonary variables between groups or within groups before or after induction. The propofol doses for induction of anesthesia were significantly different between groups, 1.9 ± 0.5 and 1.1 ± 0.5 mg kg Midazolam co-induction reduced the propofol induction dose and improved the quality of induction in critically ill dogs without an improvement in cardiopulmonary variables, when compared with a higher dose of propofol alone.

Identifiants

pubmed: 32402602
pii: S1467-2987(20)30071-4
doi: 10.1016/j.vaa.2020.03.006
pii:
doi:

Substances chimiques

Anesthetics, Combined 0
Anesthetics, Intravenous 0
Midazolam R60L0SM5BC
Propofol YI7VU623SF

Types de publication

Journal Article Randomized Controlled Trial, Veterinary

Langues

eng

Sous-ensembles de citation

IM

Pagination

472-480

Informations de copyright

Crown Copyright © 2020. Published by Elsevier Ltd. All rights reserved.

Auteurs

Rodrigo Aguilera (R)

Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada. Electronic address: rodrigo.h.aguilera@gmail.com.

Melissa Sinclair (M)

Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.

Alexander Valverde (A)

Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.

Shane Bateman (S)

Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.

Brad Hanna (B)

Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.

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Classifications MeSH