Oral Contraceptives in Dermatology.

Anticonceptivos orales en dermatología.
Contraceptives, Oral Dermatology Ethinyl Estradiol / adverse effects Female Humans Levonorgestrel Pregnancy Progesterone
Acne Acné Anticonceptivos orales Contraceptives oral Hiperandrogenismo Hirsutism Hirsutismo Hyperandrogenism

Journal

Actas dermo-sifiliograficas
ISSN: 2173-5778
Titre abrégé: Actas Dermosifiliogr (Engl Ed)
Pays: Spain
ID NLM: 101777537

Informations de publication

Date de publication:
Jun 2020
Historique:
received: 10 05 2019
revised: 31 05 2019
accepted: 03 06 2019
pubmed: 15 5 2020
medline: 25 6 2021
entrez: 15 5 2020
Statut: ppublish

Résumé

Oral contraceptives combine estrogen and progesterone to suppress ovulation. Synthetic forms are usually used. In dermatology, oral contraceptives are prescribed for 2 main reasons: to prevent pregnancy when teratogenic drugs must be taken and to treat skin manifestations of hyperandrogenism. Most oral contraceptives improve both acne and hirsutism, but the androgenic effect of progestogens - particularly if the contraceptive contains first- or second-generation progestogens- can trigger or exacerbate acne. One of the most serious side effects of oral contraceptives, thrombosis, is mainly caused by the estrogen component and its dose. If we mainly consider a contraceptive's thrombotic profile when prescribing, the choice would be to have 30μg or less of ethinyl estradiol combined with levonorgestrel. On the other hand, if our main objective is to treat signs of androgenization, we would prefer contraceptives containing progestogens with antiandrogenic effects.

Identifiants

DOI: 10.1016/j.ad.2019.06.006 PMID: 32404240
pubmed: 32404240
pii: S0001-7310(20)30055-7
doi: 10.1016/j.ad.2019.06.006
pii:
doi:

Substances chimiques

Contraceptives, Oral 0
Ethinyl Estradiol 423D2T571U
Progesterone 4G7DS2Q64Y
Levonorgestrel 5W7SIA7YZW

Types de publication

Journal Article Review

Langues

eng spa

Sous-ensembles de citation

IM

Pagination

351-356

Informations de copyright

Copyright © 2020. Publicado por Elsevier España, S.L.U.

Auteurs

C Requena (C)

Servicio de Dermatología, Instituto Valenciano de Oncología, Valencia, España. Electronic address: celiareq@hotmail.com.

B Llombart (B)

Servicio de Dermatología, Instituto Valenciano de Oncología, Valencia, España.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents régulateurs de la reproduction › Contraceptifs › Contraceptifs féminins › Contraceptifs oraux › Oral Contraceptives in Dermatology.
questionsmedicales.fr › Professions de santé › Médecine › Dermatologie › Oral Contraceptives in Dermatology.
questionsmedicales.fr › Hormones gonadiques › Hormones sexuelles stéroïdiennes › Congénères de l'oestradiol › Stéroïdes oestrogéniques à chaîne alkyle › Éthinyloestradiol › Oral Contraceptives in Dermatology.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Oral Contraceptives in Dermatology.
questionsmedicales.fr › Composés polycycliques › Composés à cycles fusionnés › Stéroïdes › Norstéroïdes › Norprégnanes › Norprégnènes › Norgestrel › Lévonorgestrel › Oral Contraceptives in Dermatology.
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Oral Contraceptives in Dermatology.
questionsmedicales.fr › Hormones gonadiques › Hormones sexuelles stéroïdiennes › Congénères de la progestérone › Progestérone › Oral Contraceptives in Dermatology.