Animal Models of Ocular Tuberculosis: Implications for Diagnosis and Treatment.

Tuberculosis animal model ocular pathogenesis uveitis

Journal

Ocular immunology and inflammation
ISSN: 1744-5078
Titre abrégé: Ocul Immunol Inflamm
Pays: England
ID NLM: 9312169

Informations de publication

Date de publication:
17 Nov 2021
Historique:
pubmed: 15 5 2020
medline: 26 2 2022
entrez: 15 5 2020
Statut: ppublish

Résumé

The pathogenesis of ocular tuberculosis (TB) has remained unclear due to the challenges of performing mechanistic studies on clinical samples. Animal models have the potential to bridge these gaps by providing information about ocular dissemination and localization of mycobacteria, innate and adaptive immune response, and granuloma formation in the eye. Here, we critically review various animal models of ocular TB from the early 20

Identifiants

pubmed: 32407249
doi: 10.1080/09273948.2020.1746358
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1513-1519

Auteurs

Soumyava Basu (S)

Retina and Uveitis Services, L V Prasad Eye Institute (MTC Campus), Bhubaneswar, India.

Narsing Rao (N)

Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Paul Elkington (P)

NIHR Biomedical Research Centre, School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.

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Classifications MeSH