Impeller geometry definition of the transventricular assist device.


Journal

Artificial organs
ISSN: 1525-1594
Titre abrégé: Artif Organs
Pays: United States
ID NLM: 7802778

Informations de publication

Date de publication:
Aug 2020
Historique:
received: 14 06 2019
revised: 10 04 2020
accepted: 14 04 2020
pubmed: 16 5 2020
medline: 3 6 2021
entrez: 16 5 2020
Statut: ppublish

Résumé

According to the World Health Organization, cardiovascular disease is the number one cause of death worldwide, except Africa, where Acquired Immune Deficiency Syndrome is the leading cause of death. In this scenario, the ventricular assist device (VAD) remains the unique alternative to extend patient life until heart transplantation. At Dante Pazzanese Institute of Cardiology, the research and development of an axial flow VAD to be fully implantable within the heart was started. This pump, denominated Transventricular Assist Device (TVAD), can be surgically implanted through a small left intercostal incision in a minimally invasive manner. The goal of this work is to analyze the impeller geometries of the TVAD, to avoid high shear stresses in the fluid and aim for the best conditions to support the circulatory system using computational fluid dynamics and in vitro tests. Different rotor geometries were selected according to the literature; based on the results, the best rotor was elected. This rotor contains a pair of spiral blades of constant and relatively high pitch, which pumps liquid at a flow rate of 3 L/min at 73 mm Hg. It is also expected that this rotor presents a moderate hemolysis since the shear rate is acceptable.

Identifiants

pubmed: 32410254
doi: 10.1111/aor.13708
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

803-810

Informations de copyright

© 2020 International Center for Artificial Organ and Transplantation and Wiley Periodicals LLC.

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Auteurs

Gustavo de Andrade (G)

CEAC, Instituto Dante Pazzanese de Cardiologia, Sao Paulo, Brazil.
Polytechnic School of the University of São Paulo (EPUSP), Sao Paulo, Brazil.

Oswaldo Horikawa (O)

CEAC, Instituto Dante Pazzanese de Cardiologia, Sao Paulo, Brazil.

Evandro Drigo (E)

CEAC, Instituto Dante Pazzanese de Cardiologia, Sao Paulo, Brazil.

Aron Andrade (A)

CEAC, Instituto Dante Pazzanese de Cardiologia, Sao Paulo, Brazil.

Jose Cardoso (J)

CEAC, Instituto Dante Pazzanese de Cardiologia, Sao Paulo, Brazil.

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