Clinical characteristics of 60 discharged cases of 2019 novel coronavirus-infected pneumonia in Taizhou, China.

2019 novel coronavirus (COVID-19) 2019 novel coronavirus-infection pneumonia (COVID-19-infection pneumonia antiviral early treatment

Journal

Annals of translational medicine
ISSN: 2305-5839
Titre abrégé: Ann Transl Med
Pays: China
ID NLM: 101617978

Informations de publication

Date de publication:
Apr 2020
Historique:
entrez: 16 5 2020
pubmed: 16 5 2020
medline: 16 5 2020
Statut: ppublish

Résumé

The number of patients with pneumonia stemming from the 2019 novel coronavirus (COVID-19) infection has increased rapidly. However, the clinical characteristics of discharged patients remain little known. Here, we attempt to describe the clinical characteristics and treatment experiences of discharged cases from Taizhou, China. A total of 60 patients with COVID-19-infected pneumonia who were discharged from Taizhou Enze Medical Center (Group), from January 31, 2020, to February 16, 2020, were included in the analysis. The discharge criteria were based on the New Coronavirus Pneumonia Prevention and Control Program (Fifth Edition, China). Of the 60 patients, the median age was 41 years, and 58.3% were male. Only 13.3% of patients were identified as having severe novel coronavirus pneumonia. All patients received combined antiviral treatment on admission, including β-interferon, lopinavir/tonavir, Abidol and oseltamivir. All patients with severe conditions received gamma globulin and hormone therapy. No patients had endotracheal intubation or died. The median duration from symptom onset to hospitalization was 3 (range, 0-15) days. The median duration of COVID-19 shedding was 14 (range, 5-26) days, and the median duration of hospital stay was 15 (range, 7-23) days. Early therapy and comprehensive therapy are key to the outcome for patients with COVID-19-infected pneumonia, especially for those with severe pneumonia. ChiCTR2000029866.

Sections du résumé

BACKGROUND BACKGROUND
The number of patients with pneumonia stemming from the 2019 novel coronavirus (COVID-19) infection has increased rapidly. However, the clinical characteristics of discharged patients remain little known. Here, we attempt to describe the clinical characteristics and treatment experiences of discharged cases from Taizhou, China.
METHODS METHODS
A total of 60 patients with COVID-19-infected pneumonia who were discharged from Taizhou Enze Medical Center (Group), from January 31, 2020, to February 16, 2020, were included in the analysis. The discharge criteria were based on the New Coronavirus Pneumonia Prevention and Control Program (Fifth Edition, China).
RESULTS RESULTS
Of the 60 patients, the median age was 41 years, and 58.3% were male. Only 13.3% of patients were identified as having severe novel coronavirus pneumonia. All patients received combined antiviral treatment on admission, including β-interferon, lopinavir/tonavir, Abidol and oseltamivir. All patients with severe conditions received gamma globulin and hormone therapy. No patients had endotracheal intubation or died. The median duration from symptom onset to hospitalization was 3 (range, 0-15) days. The median duration of COVID-19 shedding was 14 (range, 5-26) days, and the median duration of hospital stay was 15 (range, 7-23) days.
CONCLUSIONS CONCLUSIONS
Early therapy and comprehensive therapy are key to the outcome for patients with COVID-19-infected pneumonia, especially for those with severe pneumonia.
TRIAL REGISTRATION NUMBER BACKGROUND
ChiCTR2000029866.

Identifiants

pubmed: 32411770
doi: 10.21037/atm.2020.04.20
pii: atm-08-08-547
pmc: PMC7214894
doi:

Types de publication

Journal Article

Langues

eng

Pagination

547

Informations de copyright

2020 Annals of Translational Medicine. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/atm.2020.04.20). The authors have no conflicts of interest to declare.

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Auteurs

Yongpo Jiang (Y)

Department of Critical Care Medicine, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou 317000, China.

Susu He (S)

Department of Respiratory Medicine, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou 317000, China.

Chao Zhang (C)

Department of Critical Care Medicine, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou 317000, China.

Xiaodan Wang (X)

Department of Anesthesiology, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou 317000, China.

Xi Chen (X)

Department of Respiratory Medicine, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou 317000, China.

Yingying Jin (Y)

Department of Critical Care Medicine, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou 317000, China.

Zebao He (Z)

Department of Infectious Diseases, Taizhou Enze Medical Center (Group) Enze Hospital, Taizhou Public Health Center, Taizhou 318050, China.

Minjie Cai (M)

Department of Critical Care Medicine, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou 317000, China.

Zongmei Lin (Z)

Department of Infectious Diseases, Taizhou Enze Medical Center (Group) Enze Hospital, Taizhou Public Health Center, Taizhou 318050, China.

Lingjun Ying (L)

Department of Infectious Diseases, Taizhou Enze Medical Center (Group) Enze Hospital, Taizhou Public Health Center, Taizhou 318050, China.

Jianli Mou (J)

Department of Infectious Diseases, Taizhou Enze Medical Center (Group) Enze Hospital, Taizhou Public Health Center, Taizhou 318050, China.

Haihong Zhao (H)

Department of Infectious Diseases, Taizhou Enze Medical Center (Group) Enze Hospital, Taizhou Public Health Center, Taizhou 318050, China.

Ronghai Lin (R)

Department of Critical Care Medicine, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou 317000, China.

Sheng Zhang (S)

Department of Critical Care Medicine, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou 317000, China.

Xiaomai Wu (X)

Department of Respiratory Medicine, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou 317000, China.

Haixiao Chen (H)

Department of orthopedics, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou 317000, China.

Dongqing Lv (D)

Department of Respiratory Medicine, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou 317000, China.

Classifications MeSH