Comparison of Sheep, Goats, and Calves as Infection Models for Mycobacterium avium subsp. paratuberculosis.
Animals
Animals, Newborn
Antigens, Bacterial
/ pharmacology
Cattle
/ microbiology
Cytokines
/ immunology
Disease Models, Animal
Feces
/ microbiology
Goats
/ microbiology
Interferon-gamma
/ immunology
Leukocytes, Mononuclear
/ drug effects
Mycobacterium avium subsp. paratuberculosis
Paratuberculosis
/ immunology
Sheep
/ microbiology
Mycobacterium aviumsubsp. paratuberculosis
calves
goats
immunity
infection
sheep
Journal
Veterinary immunology and immunopathology
ISSN: 1873-2534
Titre abrégé: Vet Immunol Immunopathol
Pays: Netherlands
ID NLM: 8002006
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
06
02
2020
revised:
20
04
2020
accepted:
21
04
2020
pubmed:
16
5
2020
medline:
2
2
2021
entrez:
16
5
2020
Statut:
ppublish
Résumé
Animal infection models to study Mycobacterium avium subsp. paratuberculosis (MAP) infection are useful for evaluating the efficacy of vaccines and other therapeutics for the prevention or treatment of infection. The goal of the present study was to compare smaller ruminants, sheep and goats, with calves as infection models. Neonatal sheep, goats, and calves (n = 4) received 10
Identifiants
pubmed: 32413513
pii: S0165-2427(20)30086-6
doi: 10.1016/j.vetimm.2020.110060
pii:
doi:
Substances chimiques
Antigens, Bacterial
0
Cytokines
0
Interferon-gamma
82115-62-6
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
110060Informations de copyright
Published by Elsevier B.V.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare no conflict of interest with respect to the research, authorship, and/or publication of this article. Mention of tradenames or commercial products is solely for the purpose of providing specific information and does not imply recommendation or endorsement by the US Department of Agriculture.