Outcome of methotrexate treatment for ectopic pregnancies among obese women.
body surface area
ectopic pregnancy
human chorionic gonadotrophin
methotrexate
obesity
treatment success
Journal
Journal of gynecology obstetrics and human reproduction
ISSN: 2468-7847
Titre abrégé: J Gynecol Obstet Hum Reprod
Pays: France
ID NLM: 101701588
Informations de publication
Date de publication:
12 May 2020
12 May 2020
Historique:
received:
02
04
2020
revised:
28
04
2020
accepted:
29
04
2020
pubmed:
16
5
2020
medline:
16
5
2020
entrez:
16
5
2020
Statut:
aheadofprint
Résumé
Single dose administration of methotrexate (MTX) is considered the first line of treatment in selected patients with an ectopic pregnancy (EP). However, data regarding MTX efficacy among obese patients is limited. We sought to investigate the efficacy of MTX single dose regimen among obese patients MATERIAL AND METHODS: A retrospective cohort study conducted at a gynecology department in a tertiary teaching hospital, between January 2010 and December 2018, including women diagnosed with an EP and treated by a single-dose regimen of MTX. We compared success rate and gestation characteristics between obese and non-obese women. Overall, 195 women were treated with single-dose intramuscular MTX for EP during the study period. Of those, 31 women (15.9%) were obese (BMI ≥ 30 kg/m Single-dose MTX treatment among obese patients diagnosed with ectopic pregnancy led to similar success rates as compared to non-obese patients.
Identifiants
pubmed: 32413523
pii: S2468-7847(20)30133-1
doi: 10.1016/j.jogoh.2020.101790
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
101790Informations de copyright
Copyright © 2020 Elsevier Masson SAS. All rights reserved.