Biomechanical comparison of biodegradable magnesium screws and titanium screws for operative stabilization of displaced capitellar fractures.


Journal

Journal of shoulder and elbow surgery
ISSN: 1532-6500
Titre abrégé: J Shoulder Elbow Surg
Pays: United States
ID NLM: 9206499

Informations de publication

Date de publication:
Sep 2020
Historique:
received: 11 11 2019
revised: 31 01 2020
accepted: 11 02 2020
pubmed: 18 5 2020
medline: 14 1 2021
entrez: 18 5 2020
Statut: ppublish

Résumé

Displaced fractures of the humeral capitellum are commonly treated operatively and fixed by titanium screws (TSs) either directly or indirectly. In the case of direct transcartilaginous fixation, biodegradable screws with the ability to be countersunk can be favorable regarding implant impingement and cartilage destruction. Hence, the goal of this study was to biomechanically compare headless compression screws made from titanium with a biodegradable equivalent made from a magnesium alloy. This biomechanical in vitro study was conducted on 13 pairs of fresh-frozen human cadaveric humeri, in which a standardized Bryan-Morrey type I fracture was fixed using 2 magnesium screws (MSs) or 2 TSs. First, construct stiffness was measured during 10 cycles of static loading between 10 and 50 N. Second, continuous loading was applied at 4 Hz between 10 and 50 N, increasing the maximum load every 10,000 cycles by 25 N until construct failure occurred. This was defined by fragment displacement >3 mm. Comparison of the 2 screw types showed no differences related to construct stiffness (0.50 ± 0.25 kN/mm in MS group and 0.47 ± 0.13 kN/mm in TS group, P = .701), failure cycle (43,944 ± 21,625 and 41,202 ± 16,457, respectively; P = .701), and load to failure (152 ± 53 N and 150 ± 42 N, respectively; P = .915). Biomechanical comparison showed that simple capitellar fractures are equally stabilized by headless compression screws made from titanium or a biodegradable magnesium alloy. Therefore, in view of the advantages of biodegradable implants for transcartilaginous fracture stabilization, their clinical application should be considered and evaluated.

Sections du résumé

BACKGROUND BACKGROUND
Displaced fractures of the humeral capitellum are commonly treated operatively and fixed by titanium screws (TSs) either directly or indirectly. In the case of direct transcartilaginous fixation, biodegradable screws with the ability to be countersunk can be favorable regarding implant impingement and cartilage destruction. Hence, the goal of this study was to biomechanically compare headless compression screws made from titanium with a biodegradable equivalent made from a magnesium alloy.
METHODS METHODS
This biomechanical in vitro study was conducted on 13 pairs of fresh-frozen human cadaveric humeri, in which a standardized Bryan-Morrey type I fracture was fixed using 2 magnesium screws (MSs) or 2 TSs. First, construct stiffness was measured during 10 cycles of static loading between 10 and 50 N. Second, continuous loading was applied at 4 Hz between 10 and 50 N, increasing the maximum load every 10,000 cycles by 25 N until construct failure occurred. This was defined by fragment displacement >3 mm.
RESULTS RESULTS
Comparison of the 2 screw types showed no differences related to construct stiffness (0.50 ± 0.25 kN/mm in MS group and 0.47 ± 0.13 kN/mm in TS group, P = .701), failure cycle (43,944 ± 21,625 and 41,202 ± 16,457, respectively; P = .701), and load to failure (152 ± 53 N and 150 ± 42 N, respectively; P = .915).
CONCLUSION CONCLUSIONS
Biomechanical comparison showed that simple capitellar fractures are equally stabilized by headless compression screws made from titanium or a biodegradable magnesium alloy. Therefore, in view of the advantages of biodegradable implants for transcartilaginous fracture stabilization, their clinical application should be considered and evaluated.

Identifiants

pubmed: 32417047
pii: S1058-2746(20)30210-X
doi: 10.1016/j.jse.2020.02.009
pii:
doi:

Substances chimiques

Titanium D1JT611TNE
Magnesium I38ZP9992A

Types de publication

Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1912-1919

Informations de copyright

Copyright © 2020 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

Auteurs

Ferdinand C Wagner (FC)

Faculty of Medicine, Department of Orthopedics and Trauma Surgery, Medical Center, Albert Ludwig University of Freiburg, Freiburg, Germany; GERN Gewebeersatz, Regeneration and Neogenese (Tissue Replacement, Regeneration & Neogenesis), Faculty of Medicine, Department of Orthopedics and Trauma Surgery, Medical Center, Albert Ludwig University of Freiburg, Freiburg, Germany. Electronic address: ferdinand.wagner@uniklinik-freiburg.de.

Andreas Post (A)

GERN Gewebeersatz, Regeneration and Neogenese (Tissue Replacement, Regeneration & Neogenesis), Faculty of Medicine, Department of Orthopedics and Trauma Surgery, Medical Center, Albert Ludwig University of Freiburg, Freiburg, Germany.

Tayfun Yilmaz (T)

Faculty of Medicine, Department of Orthopedics and Trauma Surgery, Medical Center, Albert Ludwig University of Freiburg, Freiburg, Germany.

Dirk Maier (D)

Faculty of Medicine, Department of Orthopedics and Trauma Surgery, Medical Center, Albert Ludwig University of Freiburg, Freiburg, Germany.

Jakob Neubauer (J)

Faculty of Medicine, Department of Radiology, Medical Center, Albert Ludwig University of Freiburg, Freiburg, Germany.

Matthias J Feucht (MJ)

Faculty of Medicine, Department of Orthopedics and Trauma Surgery, Medical Center, Albert Ludwig University of Freiburg, Freiburg, Germany; Department of Orthopaedic Sports Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.

Norbert P Südkamp (NP)

Faculty of Medicine, Department of Orthopedics and Trauma Surgery, Medical Center, Albert Ludwig University of Freiburg, Freiburg, Germany; GERN Gewebeersatz, Regeneration and Neogenese (Tissue Replacement, Regeneration & Neogenesis), Faculty of Medicine, Department of Orthopedics and Trauma Surgery, Medical Center, Albert Ludwig University of Freiburg, Freiburg, Germany.

Kilian Reising (K)

Faculty of Medicine, Department of Orthopedics and Trauma Surgery, Medical Center, Albert Ludwig University of Freiburg, Freiburg, Germany; Department of Trauma Surgery, Asklepios Klinikum Hamburg, Hamburg, Germany.

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Classifications MeSH