Breakthroughs in the Use of Inositols for Assisted Reproductive Treatment (ART).

Female Fertilization in Vitro / methods Humans Inositol / therapeutic use Male Polycystic Ovary Syndrome / drug therapy Reproductive Techniques, Assisted
D-chiro-inositol, polycystic ovary syndrome assisted reproductive treatment in vitro fertilization infertility myo-inositol

Journal

Trends in endocrinology and metabolism: TEM
ISSN: 1879-3061
Titre abrégé: Trends Endocrinol Metab
Pays: United States
ID NLM: 9001516

Informations de publication

Date de publication:
08 2020
Historique:
received: 01 10 2019
revised: 27 03 2020
accepted: 13 04 2020
pubmed: 19 5 2020
medline: 10 8 2021
entrez: 19 5 2020
Statut: ppublish

Résumé

It is well known that myo-inositol (MI) and D-chiro-inositol (DCI) are insulin-sensitizing agents, and MI is of proven utility in polycystic ovary syndrome (PCOS). In addition, MI plays a pivotal role in the physiology of reproduction, and has beneficial effects on the development of oocytes, spermatozoa, and embryos. By contrast, DCI has little effect on spermatozoa, but high concentrations in the ovary can negatively affect the quality of oocytes and the blastocyst. Overall, the evidence in the literature supports the beneficial effects of MI in both female and male reproduction, warranting clinical use of MI in assisted reproductive treatment (ART).

Identifiants

DOI: 10.1016/j.tem.2020.04.003 PMID: 32418772
pubmed: 32418772
pii: S1043-2760(20)30080-1
doi: 10.1016/j.tem.2020.04.003
pii:
doi:

Substances chimiques

Inositol 4L6452S749

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

570-579

Investigateurs

Fabio Facchinetti (F)
Vittorio Unfer (V)
Marialuisa Appetecchia (M)
Cesare Aragona (C)
Matteo Bertelli (M)
Arturo Bevilacqua (A)
Maria Salome Bezerra Espinola (MSB)
Mariano Bizzarri (M)
Pietro Cavalli (P)
Andrew Copp (A)
Rosario D'Anna (R)
Didier Dewailly (D)
Nicholas Greene (N)
Imelda Hernández Marín (IH)
Zdravko A Kamenov (ZA)
Eleni Kandaraki (E)
Evanthia Diamanti-Kandarakis (E)
Antonio Simone Laganà (AS)
Giovanni Monastra (G)
Mario Montanino Oliva (MM)
John E Nestler (JE)
Ali Cenk Ozay (AC)
Olga Papalou (O)
Lali Pkhaladze (L)
Giusy Porcaro (G)
Nikos Prapas (N)
Christophe O Soulage (CO)
Annarita Stringaro (A)
Mónica Vazquez-Levin (M)
Artur Wdowiak (A)

Informations de copyright

Copyright © 2020. Published by Elsevier Ltd.

Auteurs

Fabio Facchinetti (F)

Mother-Infant Department, University of Modena and Reggio Emilia, Modena, Italy.

Maria Salome Bezerra Espinola (MSB)

Systems Biology Laboratory, Department of Experimental Medicine, Sapienza University, Rome, Italy.

Didier Dewailly (D)

Faculty of Medicine, University of Lille, and Institut National de la Santé et de la Recherche Médicale (INSERM) Laboratory of Development and Plasticity of the Neuroendocrine Brain, Jean-Pierre Aubert Research Centre, Lille, France.

Ali Cenk Ozay (AC)

Near East University, Faculty of Medicine, Department of Obstetrics and Gynecology, and Research Center of Experimental Health Sciences, Nicosia, Cyprus.

Nikos Prapas (N)

Third Department of OB-GYNAE, Aristotle University of Thessaloniki, and IVF Laboratory, IAKENTRO Fertility Centre, Thessaloniki, Greece.

Mónica Vazquez-Levin (M)

National Council of Scientific and Technical Research, Instituto de Biología y Medicina Experimental (IBYME), Buenos Aires, Argentina.

Artur Wdowiak (A)

Diagnostic Techniques Unit, Medical University of Lublin, Poland.

Vittorio Unfer (V)

Department of Experimental Medicine, Sapienza University, Rome, Italy. Electronic address: vunfer@gmail.com.

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Classifications MeSH

questionsmedicales.fr › Techniques d'investigation › Techniques de reproduction › Techniques de reproduction assistée › Fécondation in vitro › Breakthroughs in the Use of Inositols for...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Breakthroughs in the Use of Inositols for...
questionsmedicales.fr › Glucides › Polyols › Inositol › Breakthroughs in the Use of Inositols for...
questionsmedicales.fr › Maladies endocriniennes › Troubles gonadiques › Maladies ovariennes › Kystes de l'ovaire › Syndrome des ovaires polykystiques › Breakthroughs in the Use of Inositols for...
questionsmedicales.fr › Techniques d'investigation › Techniques de reproduction › Techniques de reproduction assistée › Breakthroughs in the Use of Inositols for...