Interactions of Perfluorooctanesulfonate and 6:2 Chlorinated Polyfluorinated Ether Sulfonate with Human Serum Albumin: A Comparative Study.
Journal
Chemical research in toxicology
ISSN: 1520-5010
Titre abrégé: Chem Res Toxicol
Pays: United States
ID NLM: 8807448
Informations de publication
Date de publication:
15 06 2020
15 06 2020
Historique:
pubmed:
20
5
2020
medline:
8
7
2021
entrez:
20
5
2020
Statut:
ppublish
Résumé
6:2 Chlorinated polyfluorinated ether sulfonate (6:2 Cl-PFESA) possesses a similar structure to perfluorooctanesulfonate (PFOS) and is the third most important polyfluoroalkyl/perfluoroalkyl substance (PFAS) found in the general population of China. Studies have indicated that 6:2 Cl-PFESA exhibits a stronger bioaccumulative and toxicological potential than PFOS and is thus of considerable environmental concern. Here, the binding characteristics of PFOS and 6:2 Cl-PFESA to human serum albumin (HSA) were explored based on
Identifiants
pubmed: 32423201
doi: 10.1021/acs.chemrestox.0c00075
doi:
Substances chimiques
Alkanesulfonic Acids
0
Ethers
0
Fluorocarbons
0
perfluorooctane sulfonic acid
9H2MAI21CL
Serum Albumin, Human
ZIF514RVZR
Types de publication
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM