H


Journal

Monoclonal antibodies in immunodiagnosis and immunotherapy
ISSN: 2167-9436
Titre abrégé: Monoclon Antib Immunodiagn Immunother
Pays: United States
ID NLM: 101590955

Informations de publication

Date de publication:
Jun 2020
Historique:
pubmed: 20 5 2020
medline: 23 4 2021
entrez: 20 5 2020
Statut: ppublish

Résumé

Overexpression of human epidermal growth factor receptor 2 (HER2) has been reported in breast cancer, gastric, lung, colorectal, oral, and pancreatic cancers. HER2 expression is associated with poor clinical outcomes. An anti-HER2 humanized antibody, trastuzumab, has improved survival rates in patients with HER2-overexpressing breast and gastric cancers. Previously, we established a novel anti-HER2 monoclonal antibody (mAb), H

Identifiants

pubmed: 32423281
doi: 10.1089/mab.2020.0011
doi:

Substances chimiques

Antibodies, Monoclonal, Humanized 0
Immunoglobulin G 0
ERBB2 protein, human EC 2.7.10.1
Receptor, ErbB-2 EC 2.7.10.1

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

61-65

Auteurs

Yukinari Kato (Y)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.
New Industry Creation Hatchery Center, Tohoku University, Sendai, Japan.

Tomokazu Ohishi (T)

Institute of Microbial Chemistry (BIKAKEN), Numazu, Microbial Chemistry Research Foundation, Numazu-shi, Japan.

Masato Sano (M)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Teizo Asano (T)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Yusuke Sayama (Y)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Junko Takei (J)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Manabu Kawada (M)

Institute of Microbial Chemistry (BIKAKEN), Numazu, Microbial Chemistry Research Foundation, Numazu-shi, Japan.

Mika K Kaneko (MK)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

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Classifications MeSH