Clinical characteristics and changes of chest CT features in 307 patients with common COVID-19 pneumonia infected SARS-CoV-2: A multicenter study in Jiangsu, China.
COVID-19
CT
SARS-CoV-2
change
chest
Journal
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
ISSN: 1878-3511
Titre abrégé: Int J Infect Dis
Pays: Canada
ID NLM: 9610933
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
22
03
2020
revised:
29
04
2020
accepted:
01
05
2020
pubmed:
20
5
2020
medline:
29
7
2020
entrez:
20
5
2020
Statut:
ppublish
Résumé
The study was aimed to describe the clinical characteristics and evaluate the dynamic changes of chest CT features in the first three weeks in the common type fo COVID-19 pneumonia patients in Jiangsu Province. 307 patients infected SARS-CoV-2 classified as common type were enrolled in the study. 628 chest CT scans were divided into three groups based on the time interval between symptoms and chest CT scan. The clinical characteristics were descriptively analyzed.The chest CT features were quantitatively evaluated. Mann-Whitney U test was used to test the differences in three groups and between men and women. Spearman rank correlation was used to test the association between the arterial blood gas(ABG) analysis results and chest CT scores. Fever (69.1%) and cough (62.8%) were common symptoms. 111(36.2%) patients were anorexia. GGO was the most common manifestation of COVID-19 pneumonia, which could be followed by consolidation and fibrosis. Lower lobe or subpleural region was the most common distribution form of lesion. More lung lobes were involved in the third week. Total chest CT scores in the second week were higher than the first week. Fibrosis Scores increased in the second and third week. Total CT score, GGO score and fibrosis score of male patients were significantly higher than female in the second week. Male patients had higher consolidation score and fibrosis score than female in the third week. Total CT score and GGO score had weak to moderate correlation with arterial blood gas indices. Changes in chest CT were difficult to assess quantitatively in the first third weeks. Male patients recovered slower than female in the second week. Although CT score had correlations with arterial blood gas indices, long-term follow-up of pulmonary function test is needed to determine the recovery of lung.
Identifiants
pubmed: 32423888
pii: S1201-9712(20)30312-X
doi: 10.1016/j.ijid.2020.05.006
pmc: PMC7207103
pii:
doi:
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
157-162Informations de copyright
Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Références
Lancet Respir Med. 2020 Apr;8(4):420-422
pubmed: 32085846
Lancet Glob Health. 2020 Apr;8(4):e488-e496
pubmed: 32119825
J Infect. 2020 Apr;80(4):388-393
pubmed: 32112884
Radiology. 2020 Apr;295(1):16-17
pubmed: 32017662
Int J Surg. 2020 Apr;76:71-76
pubmed: 32112977
J Autoimmun. 2020 May;109:102433
pubmed: 32113704
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Lancet Infect Dis. 2020 Apr;20(4):425-434
pubmed: 32105637
Transfus Med Rev. 2020 Apr;34(2):75-80
pubmed: 32107119
Eur Radiol. 2020 Jul;30(7):3612-3613
pubmed: 32025790
Eur J Radiol. 2020 May;126:108941
pubmed: 32193037