Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis.
Animals
Biomarkers
Cell Transformation, Neoplastic
/ genetics
Connective Tissue Growth Factor
/ genetics
Disease Models, Animal
Epidermis
/ metabolism
Fluorescent Antibody Technique
Gene Expression
Gene Expression Regulation
Hair Follicle
/ cytology
Immunohistochemistry
Immunophenotyping
Integrin alpha3beta1
/ genetics
Keratinocytes
/ metabolism
Mice
Mice, Knockout
Neoplasm Staging
Skin Neoplasms
/ etiology
Stem Cells
/ metabolism
Journal
Life science alliance
ISSN: 2575-1077
Titre abrégé: Life Sci Alliance
Pays: United States
ID NLM: 101728869
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
received:
13
01
2020
revised:
06
05
2020
accepted:
06
05
2020
entrez:
20
5
2020
pubmed:
20
5
2020
medline:
8
7
2021
Statut:
epublish
Résumé
Epidermal-specific deletion of integrin α3β1 almost completely prevents the formation of papillomas during 7,12-Dimethylbenz[
Identifiants
pubmed: 32423907
pii: 3/7/e202000645
doi: 10.26508/lsa.202000645
pmc: PMC7240742
pii:
doi:
Substances chimiques
Biomarkers
0
CCN2 protein, mouse
0
Integrin alpha3beta1
0
Connective Tissue Growth Factor
139568-91-5
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2020 Ramovs et al.
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