Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses.

BRCA1 Protein / genetics Breast Neoplasms / genetics Case-Control Studies Female Genetic Predisposition to Disease Genome-Wide Association Study Humans Linkage Disequilibrium Mutation Triple Negative Breast Neoplasms / genetics

Journal

Nature genetics
ISSN: 1546-1718
Titre abrégé: Nat Genet
Pays: United States
ID NLM: 9216904

Informations de publication

Date de publication:
06 2020
Historique:
received: 23 09 2019
accepted: 05 03 2020
pubmed: 20 5 2020
medline: 2 9 2020
entrez: 20 5 2020
Statut: ppublish

Résumé

Breast cancer susceptibility variants frequently show heterogeneity in associations by tumor subtype

Identifiants

DOI: 10.1038/s41588-020-0609-2 PMID: 32424353 PMC: PMC7808397
pubmed: 32424353
doi: 10.1038/s41588-020-0609-2
pii: 10.1038/s41588-020-0609-2
pmc: PMC7808397
mid: NIHMS1572778
doi:

Substances chimiques

BRCA1 Protein 0
BRCA1 protein, human 0

Types de publication

Journal Article Meta-Analysis Research Support, N.I.H., Extramural Research Support, N.I.H., Intramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

572-581

Subventions

Organisme : NCI NIH HHS
ID : U10 CA180868
Pays : United States
Organisme : NCI NIH HHS
ID : UG1 CA189867
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA176785
Pays : United States
Organisme : Cancer Research UK
ID : C1287/A10710
Pays : United Kingdom
Organisme : NHGRI NIH HHS
ID : R01 HG010480
Pays : United States
Organisme : NCI NIH HHS
ID : U01 CA194393
Pays : United States
Organisme : Cancer Research UK
ID : C12292/A11174
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_12023/20
Pays : United Kingdom
Organisme : NCI NIH HHS
ID : P50 CA116201
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA023100
Pays : United States
Organisme : CIHR
ID : GPH-129344
Pays : Canada
Organisme : NCI NIH HHS
ID : U19 CA148112
Pays : United States
Organisme : NCI NIH HHS
ID : U19 CA148065
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA194393
Pays : United States
Organisme : NIEHS NIH HHS
ID : P30 ES010126
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA016672
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002538
Pays : United States
Organisme : Cancer Research UK
ID : C1287/A16563
Pays : United Kingdom
Organisme : NHLBI NIH HHS
ID : HHSN268201200008C
Pays : United States
Organisme : NCI NIH HHS
ID : U01 CA116167
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA128978
Pays : United States
Organisme : NCI NIH HHS
ID : U19 CA148537
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA116167
Pays : United States
Organisme : Cancer Research UK
ID : C12292/A20861
Pays : United Kingdom
Organisme : NIGMS NIH HHS
ID : P20 GM130423
Pays : United States
Organisme : Cancer Research UK
ID : C1287/A10118
Pays : United Kingdom
Organisme : NHLBI NIH HHS
ID : HHSN268201200008I
Pays : United States

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Auteurs

Haoyu Zhang (H)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services, Bethesda, MD, USA.
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Thomas U Ahearn (TU)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services, Bethesda, MD, USA.

Julie Lecarpentier (J)

Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.

Daniel Barnes (D)

Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
ORCID: 0000-0002-3781-7570

Jonathan Beesley (J)

Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.

Guanghao Qi (G)

Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Xia Jiang (X)

Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Tracy A O'Mara (TA)

Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
ORCID: 0000-0002-5436-3232

Ni Zhao (N)

Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Manjeet K Bolla (MK)

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

Alison M Dunning (AM)

Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
ORCID: 0000-0001-6651-7166

Joe Dennis (J)

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
ORCID: 0000-0003-4591-1214

Qin Wang (Q)

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

Zumuruda Abu Ful (ZA)

Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel.

Kristiina Aittomäki (K)

Department of Clinical Genetics, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.

Irene L Andrulis (IL)

Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
ORCID: 0000-0002-4226-6435

Hoda Anton-Culver (H)

Department of Epidemiology, Genetic Epidemiology Research Institute, University of California, Irvine, Irvine, CA, USA.

Volker Arndt (V)

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
ORCID: 0000-0001-9320-8684

Kristan J Aronson (KJ)

Department of Public Health Sciences and Cancer Research Institute, Queen's University, Kingston, Ontario, Canada.

Banu K Arun (BK)

Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Paul L Auer (PL)

Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.

Jacopo Azzollini (J)

Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy.
ORCID: 0000-0002-9364-9778

Daniel Barrowdale (D)

Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.

Heiko Becher (H)

Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Matthias W Beckmann (MW)

Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen, Germany.

Sabine Behrens (S)

Division of Cancer Epidemiology, DKFZ, Heidelberg, Germany.

Javier Benitez (J)

Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Valencia, Spain.

Marina Bermisheva (M)

Institute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia.

Katarzyna Bialkowska (K)

Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.

Ana Blanco (A)

Molecular Medicine Unit, Fundación Pública Galega de Medicina Xenómica, Santiago de Compostela, Spain.
Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, Servicio Galego de Saude (SERGAS), Santiago de Compostela, Spain.
CIBERER, Santiago de Compostela, Spain.

Carl Blomqvist (C)

Department of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Department of Oncology, Örebro University Hospital, Örebro, Sweden.

Natalia V Bogdanova (NV)

N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus.
Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.
Department of Radiation Oncology, Hannover Medical School, Hannover, Germany.

Stig E Bojesen (SE)

Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
ORCID: 0000-0002-4061-4133

Bernardo Bonanni (B)

Division of Cancer Prevention and Genetics, European Institute of Oncology (IEO) IRCCS, Milan, Italy.
ORCID: 0000-0003-3589-2128

Davide Bondavalli (D)

Division of Cancer Prevention and Genetics, European Institute of Oncology (IEO) IRCCS, Milan, Italy.

Ake Borg (A)

Department of Oncology, Lund University and Skåne University Hospital, Lund, Sweden.

Hiltrud Brauch (H)

Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.
iFIT Cluster of Excellence, University of Tübingen, Tübingen, Germany.
German Cancer Consortium (DKTK), DKFZ, Heidelberg, Germany.
ORCID: 0000-0001-7531-2736

Hermann Brenner (H)

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
German Cancer Consortium (DKTK), DKFZ, Heidelberg, Germany.
Division of Preventive Oncology, DKFZ and National Center for Tumor Diseases (NCT), Heidelberg, Germany.

Ignacio Briceno (I)

Bioscience Department, Faculty of Medicine, Universidad de la Sabana, Chia, Colombia.

Annegien Broeks (A)

Division of Molecular Pathology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.

Sara Y Brucker (SY)

Department of Women's Health, University of Tübingen, Tübingen, Germany.

Thomas Brüning (T)

Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Ruhr University Bochum, Bochum, Germany.

Barbara Burwinkel (B)

Molecular Epidemiology Group (C080), DKFZ, Heidelberg, Germany.
Molecular Biology of Breast Cancer, University Women's Clinic Heidelberg, University of Heidelberg, Heidelberg, Germany.

Saundra S Buys (SS)

Department of Medicine, Huntsman Cancer Institute, Salt Lake City, UT, USA.

Helen Byers (H)

Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester NIHR Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

Trinidad Caldés (T)

Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
ORCID: 0000-0002-1038-5392

Maria A Caligo (MA)

Section of Molecular Genetics, Department of Laboratory Medicine, University Hospital of Pisa, Pisa, Italy.

Mariarosaria Calvello (M)

Division of Cancer Prevention and Genetics, European Institute of Oncology (IEO) IRCCS, Milan, Italy.
ORCID: 0000-0003-2113-8503

Daniele Campa (D)

Division of Cancer Epidemiology, DKFZ, Heidelberg, Germany.
Department of Biology, University of Pisa, Pisa, Italy.

Jose E Castelao (JE)

Oncology and Genetics Unit, Instituto de Investigacion Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, Vigo, Spain.

Jenny Chang-Claude (J)

Division of Cancer Epidemiology, DKFZ, Heidelberg, Germany.
Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Stephen J Chanock (SJ)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services, Bethesda, MD, USA.
ORCID: 0000-0002-2324-3393

Melissa Christiaens (M)

Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium.

Hans Christiansen (H)

Department of Radiation Oncology, Hannover Medical School, Hannover, Germany.

Wendy K Chung (WK)

Departments of Pediatrics and Medicine, Columbia University, New York, NY, USA.

Kathleen B M Claes (KBM)

Centre for Medical Genetics, Ghent University, Ghent, Belgium.
ORCID: 0000-0003-0841-7372

Christine L Clarke (CL)

Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.

Sten Cornelissen (S)

Division of Molecular Pathology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.

Fergus J Couch (FJ)

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

Angela Cox (A)

Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.

Simon S Cross (SS)

Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield, UK.

Kamila Czene (K)

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

Mary B Daly (MB)

Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA, USA.

Peter Devilee (P)

Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands.
ORCID: 0000-0002-8023-2009

Orland Diez (O)

Oncogenetics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.

Susan M Domchek (SM)

Department of Medicine, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Thilo Dörk (T)

Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.
ORCID: 0000-0002-9458-0282

Miriam Dwek (M)

Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, UK.
ORCID: 0000-0001-7184-2932

Diana M Eccles (DM)

Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK.

Arif B Ekici (AB)

Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center ER-EMN, Erlangen, Germany.
ORCID: 0000-0001-6099-7066

D Gareth Evans (DG)

Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester NIHR Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Division of Evolution and Genomic Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

Peter A Fasching (PA)

Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen, Germany.
David Geffen School of Medicine, Department of Medicine, Division of Hematology and Oncology, University of California, Los Angeles, Los Angeles, CA, USA.
ORCID: 0000-0003-4885-8471

Jonine Figueroa (J)

Usher Institute of Population Health Sciences and Informatics, University of Edinburgh Medical School, Edinburgh, UK.

Lenka Foretova (L)

Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic.

Florentia Fostira (F)

Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece.

Eitan Friedman (E)

The Susanne Levy Gertner Oncogenetics Unit, Chaim Sheba Medical Center, Ramat Gan, Israel.

Debra Frost (D)

Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.

Manuela Gago-Dominguez (M)

Genomic Medicine Group, Galician Foundation of Genomic Medicine, IDIS, Complejo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.
Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.

Susan M Gapstur (SM)

Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA.

Judy Garber (J)

Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, MA, USA.

José A García-Sáenz (JA)

Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
ORCID: 0000-0001-6880-0301

Mia M Gaudet (MM)

Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA.

Simon A Gayther (SA)

Center for Bioinformatics and Functional Genomics and the Cedars-Sinai Genomics Core, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
ORCID: 0000-0001-7937-5443

Graham G Giles (GG)

Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.
Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.
Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Victoria, Australia.
ORCID: 0000-0003-4946-9099

Andrew K Godwin (AK)

Department of Pathology and Laboratory Medicine, Kansas University Medical Center, Kansas City, KS, USA.

Mark S Goldberg (MS)

Department of Medicine, McGill University, Montréal, Québec, Canada.
Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montréal, Québec, Canada.
Breast Cancer Research Unit, Cancer Research Institute, University Malaya Medical Centre, Kuala Lumpur, Malaysia.

David E Goldgar (DE)

Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.

Anna González-Neira (A)

Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

Mark H Greene (MH)

Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
ORCID: 0000-0003-1852-9239

Jacek Gronwald (J)

Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.

Pascal Guénel (P)

Cancer and Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University of Paris-Saclay, Paris, France.
ORCID: 0000-0002-8359-518X

Lothar Häberle (L)

Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center ER-EMN, Erlangen, Germany.

Eric Hahnen (E)

Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.

Christopher A Haiman (CA)

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Christopher R Hake (CR)

Waukesha Memorial Hospital Pro Health Care, Waukesha, WI, USA.

Per Hall (P)

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Department of Oncology, Södersjukhuset, Stockholm, Sweden.

Ute Hamann (U)

Molecular Genetics of Breast Cancer, DKFZ, Heidelberg, Germany.

Elaine F Harkness (EF)

Division of Informatics, Imaging and Data Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Nightingale Breast Screening Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
ORCID: 0000-0001-6625-7739

Bernadette A M Heemskerk-Gerritsen (BAM)

Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
ORCID: 0000-0002-9724-6693

Peter Hillemanns (P)

Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.

Frans B L Hogervorst (FBL)

Family Cancer Clinic, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.

Bernd Holleczek (B)

Saarland Cancer Registry, Saarbrücken, Germany.

Antoinette Hollestelle (A)

Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
ORCID: 0000-0003-1166-1966

Maartje J Hooning (MJ)

Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.

Robert N Hoover (RN)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services, Bethesda, MD, USA.

John L Hopper (JL)

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.

Anthony Howell (A)

Division of Cancer Sciences, University of Manchester, Manchester, UK.

Hanna Huebner (H)

Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen, Germany.
ORCID: 0000-0001-6889-1493

Peter J Hulick (PJ)

Center for Medical Genetics, NorthShore University HealthSystem, Evanston, IL, USA.
ORCID: 0000-0001-8397-4078

Evgeny N Imyanitov (EN)

N.N. Petrov Institute of Oncology, St. Petersburg, Russia.

Claudine Isaacs (C)

Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.

Louise Izatt (L)

Clinical Genetics, Guy's and St. Thomas' NHS Foundation Trust, London, UK.

Agnes Jager (A)

Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.

Milena Jakimovska (M)

Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', Macedonian Academy of Sciences and Arts, Skopje, Republic of Macedonia.
ORCID: 0000-0002-1506-0669

Anna Jakubowska (A)

Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, Poland.
ORCID: 0000-0002-5650-0501

Paul James (P)

Parkville Familial Cancer Centre, Peter MacCallum Cancer Center, Melbourne, Victoria, Australia.
ORCID: 0000-0002-4361-4657

Ramunas Janavicius (R)

Hematology, Oncology and Transfusion Medicine Center, Department of Molecular and Regenerative Medicine, Vilnius University Hospital Santariskiu Clinics, Vilnius, Lithuania.
State Research Institute Center for Innovative Medicine, Vilnius, Lithuania.

Wolfgang Janni (W)

Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany.

Esther M John (EM)

Department of Medicine, Division of Oncology, Stanford Cancer Institute, School of Medicine, Stanford University, Stanford, CA, USA.

Michael E Jones (ME)

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.
ORCID: 0000-0001-7479-3451

Audrey Jung (A)

Division of Cancer Epidemiology, DKFZ, Heidelberg, Germany.

Rudolf Kaaks (R)

Division of Cancer Epidemiology, DKFZ, Heidelberg, Germany.

Pooja Middha Kapoor (PM)

Division of Cancer Epidemiology, DKFZ, Heidelberg, Germany.
Faculty of Medicine, University of Heidelberg, Heidelberg, Germany.
ORCID: 0000-0001-5503-8215

Beth Y Karlan (BY)

David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California, Los Angeles, Los Angeles, CA, USA.

Renske Keeman (R)

Division of Molecular Pathology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.
ORCID: 0000-0002-5452-9933

Sofia Khan (S)

Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.

Elza Khusnutdinova (E)

Institute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia.
Department of Genetics and Fundamental Medicine, Bashkir State Medical University, Ufa, Russia.

Cari M Kitahara (CM)

Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

Yon-Dschun Ko (YD)

Department of Internal Medicine, Evangelische Kliniken Bonn, Johanniter Krankenhaus, Bonn, Germany.

Irene Konstantopoulou (I)

Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece.
ORCID: 0000-0002-0470-0309

Linetta B Koppert (LB)

Department of Surgical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.

Stella Koutros (S)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services, Bethesda, MD, USA.

Vessela N Kristensen (VN)

Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital-Radiumhospitalet, Oslo, Norway.
Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.

Anne-Vibeke Laenkholm (AV)

Department of Surgical Pathology, Zealand University Hospital, Slagelse, Denmark.

Diether Lambrechts (D)

VIB Center for Cancer Biology, VIB, Leuven, Belgium.
Laboratory of Translational Genetics, Department of Human Genetics, University of Leuven, Leuven, Belgium.

Susanna C Larsson (SC)

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
ORCID: 0000-0003-0118-0341

Pierre Laurent-Puig (P)

Université Paris Sorbonne Cité, INSERM UMR-S1147, Paris, France.
ORCID: 0000-0001-8475-5459

Conxi Lazaro (C)

Molecular Diagnostic Unit, Hereditary Cancer Program, Bellvitge Biomedical Research Institute (IDIBELL), Catalan Institute of Oncology (ICO), CIBERONC, Barcelona, Spain.

Emilija Lazarova (E)

Ss. Cyril and Methodius University in Skopje, Medical Faculty, University Clinic of Radiotherapy and Oncology, Skopje, Republic of North Macedonia.

Flavio Lejbkowicz (F)

Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel.

Goska Leslie (G)

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
ORCID: 0000-0001-5756-6222

Fabienne Lesueur (F)

Genetic Epidemiology of Cancer Team, INSERM U900, Paris, France.
ORCID: 0000-0001-7404-4549

Annika Lindblom (A)

Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden.

Jolanta Lissowska (J)

Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Cancer Center, Oncology Institute, Warsaw, Poland.
ORCID: 0000-0003-2695-5799

Wing-Yee Lo (WY)

Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.
University of Tübingen, Tübingen, Germany.

Jennifer T Loud (JT)

Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

Jan Lubinski (J)

Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.

Alicja Lukomska (A)

Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.

Robert J MacInnis (RJ)

Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.
Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.

Arto Mannermaa (A)

Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.
Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.
Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland.

Mehdi Manoochehri (M)

Molecular Genetics of Breast Cancer, DKFZ, Heidelberg, Germany.

Siranoush Manoukian (S)

Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy.

Sara Margolin (S)

Department of Oncology, Södersjukhuset, Stockholm, Sweden.
Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.

Maria Elena Martinez (ME)

Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.
Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, CA, USA.

Laura Matricardi (L)

Immunology and Molecular Oncology Unit, Veneto Institute of Oncology (IOV)-IRCCS, Padua, Italy.
ORCID: 0000-0002-0241-1810

Lesley McGuffog (L)

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

Catriona McLean (C)

Department of Anatomical Pathology, The Alfred Hospital, Melbourne, Victoria, Australia.
ORCID: 0000-0002-0302-5727

Noura Mebirouk (N)

Genetic Epidemiology of Cancer Team, INSERM U900, Institut Curie, PSL University, Mines ParisTech, Paris, France.

Alfons Meindl (A)

Department of Gynecology and Obstetrics, Ludwig Maximilian University of Munich, Munich, Germany.

Usha Menon (U)

MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK.
ORCID: 0000-0003-3708-1732

Austin Miller (A)

NRG Oncology, Statistics and Data Management Center, Roswell Park Cancer Institute, Buffalo, NY, USA.
ORCID: 0000-0001-9739-8462

Elvira Mingazheva (E)

Department of Genetics and Fundamental Medicine, Bashkir State Medical University, Ufa, Russia.

Marco Montagna (M)

Immunology and Molecular Oncology Unit, Veneto Institute of Oncology (IOV)-IRCCS, Padua, Italy.

Anna Marie Mulligan (AM)

Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada.
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

Claire Mulot (C)

Université Paris Sorbonne Cité, INSERM UMR-S1147, Paris, France.

Taru A Muranen (TA)

Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
ORCID: 0000-0002-5895-1808

Katherine L Nathanson (KL)

Department of Medicine, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
ORCID: 0000-0002-6740-0901

Susan L Neuhausen (SL)

Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA.

Heli Nevanlinna (H)

Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
ORCID: 0000-0002-0916-2976

Patrick Neven (P)

Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium.

William G Newman (WG)

Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester NIHR Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Division of Evolution and Genomic Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
ORCID: 0000-0002-6382-4678

Finn C Nielsen (FC)

Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Liene Nikitina-Zake (L)

Latvian Biomedical Research and Study Centre, Riga, Latvia.

Jesse Nodora (J)

Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.
Department of Family Medicine and Public Health, School of Medicine, University of California, San Diego, La Jolla, CA, USA.

Kenneth Offit (K)

Clinical Genetics Research Laboratory, Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Edith Olah (E)

Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary.

Olufunmilayo I Olopade (OI)

Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, USA.
Department of Clinical Pathology, University of Melbourne, Melbourne, Victoria, Australia.
ORCID: 0000-0002-9936-1599

Håkan Olsson (H)

Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden.
Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Nick Orr (N)

Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, Northern Ireland, UK.
ORCID: 0000-0003-2866-942X

Laura Papi (L)

Unit of Medical Genetics, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Florence, Italy.

Janos Papp (J)

Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary.

Tjoung-Won Park-Simon (TW)

Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.

Michael T Parsons (MT)

Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
ORCID: 0000-0003-3242-8477

Bernard Peissel (B)

Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy.

Ana Peixoto (A)

Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.

Beth Peshkin (B)

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.
ORCID: 0000-0002-2997-4701

Paolo Peterlongo (P)

Genome Diagnostics Program, IFOM, FIRC Institute of Molecular Oncology, Milan, Italy.
ORCID: 0000-0001-6951-6855

Julian Peto (J)

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
ORCID: 0000-0002-1685-8912

Kelly-Anne Phillips (KA)

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.
Peter MacCallum Cancer Center, Melbourne, Victoria, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia.

Marion Piedmonte (M)

NRG Oncology, Statistics and Data Management Center, Roswell Park Cancer Institute, Buffalo, NY, USA.

Dijana Plaseska-Karanfilska (D)

Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', Macedonian Academy of Sciences and Arts, Skopje, Republic of Macedonia.
ORCID: 0000-0001-8877-2416

Karolina Prajzendanc (K)

Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.

Ross Prentice (R)

Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Darya Prokofyeva (D)

Department of Genetics and Fundamental Medicine, Bashkir State Medical University, Ufa, Russia.

Brigitte Rack (B)

Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany.

Paolo Radice (P)

Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, INT, Milan, Italy.
ORCID: 0000-0001-6298-4111

Susan J Ramus (SJ)

Adult Cancer Program, Lowy Cancer Research Centre, University of NSW Sydney, Sydney, New South Wales, Australia.
School of Women's and Children's Health, Faculty of Medicine, University of NSW Sydney, Sydney, New South Wales, Australia.
The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Sydney, New South Wales, Australia.

Johanna Rantala (J)

Clinical Genetics, Karolinska Institutet, Stockholm, Sweden.

Muhammad U Rashid (MU)

Molecular Genetics of Breast Cancer, DKFZ, Heidelberg, Germany.
Department of Basic Sciences, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH&RC), Lahore, Pakistan.

Gad Rennert (G)

Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel.
ORCID: 0000-0002-8512-068X

Hedy S Rennert (HS)

Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel.

Harvey A Risch (HA)

Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA.

Atocha Romero (A)

Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal.
ORCID: 0000-0002-1634-7397

Matti A Rookus (MA)

Department of Epidemiology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

Matthias Rübner (M)

Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center ER-EMN, Erlangen, Germany.

Thomas Rüdiger (T)

Institute of Pathology, Staedtisches Klinikum Karlsruhe, Karlsruhe, Germany.

Emmanouil Saloustros (E)

Department of Oncology, University Hospital of Larissa, Larissa, Greece.
ORCID: 0000-0002-0485-0120

Sarah Sampson (S)

Prevent Breast Cancer Centre and Nightingale Breast Screening Centre, Manchester University NHS Foundation Trust, Manchester, UK.

Dale P Sandler (DP)

Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Durham, NC, USA.

Elinor J Sawyer (EJ)

Research Oncology, Guy's Hospital, King's College London, London, UK.

Maren T Scheuner (MT)

Cancer Genetics and Prevention Program, University of California, San Francisco, San Francisco, CA, USA.

Rita K Schmutzler (RK)

Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.

Andreas Schneeweiss (A)

Molecular Biology of Breast Cancer, University Women's Clinic Heidelberg, University of Heidelberg, Heidelberg, Germany.
NCT, University Hospital and DKFZ, Heidelberg, Germany.

Minouk J Schoemaker (MJ)

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.

Ben Schöttker (B)

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Peter Schürmann (P)

Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.

Leigha Senter (L)

Clinical Cancer Genetics Program, Division of Human Genetics, Department of Internal Medicine, Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.

Priyanka Sharma (P)

Department of Internal Medicine, Division of Oncology, University of Kansas Medical Center, Westwood, Kansas City, KS, USA.

Mark E Sherman (ME)

Department of Health Sciences Research, Mayo Clinic College of Medicine, Jacksonville, FL, USA.

Xiao-Ou Shu (XO)

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.

Christian F Singer (CF)

Department of Obstetrics and Gynecology and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

Snezhana Smichkoska (S)

Ss. Cyril and Methodius University in Skopje, Medical Faculty, University Clinic of Radiotherapy and Oncology, Skopje, Republic of North Macedonia.

Penny Soucy (P)

Genomics Center, Centre Hospitalier Universitaire de Québec-Université Laval Research Center, Québec City, Québec, Canada.

Melissa C Southey (MC)

Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Victoria, Australia.

John J Spinelli (JJ)

Population Oncology, BC Cancer, Vancouver, British Columbia, Canada.
School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada.

Jennifer Stone (J)

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.
Curtin UWA Centre for Genetic Origins of Health and Disease, Curtin University and University of Western Australia, Perth, Western Australia, Australia.
ORCID: 0000-0001-5077-0124

Dominique Stoppa-Lyonnet (D)

Department of Genetics, INSERM U830, Institut Curie, Paris Descartes Sorbonne-Paris Cité University, Paris, France.

Anthony J Swerdlow (AJ)

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.
Division of Breast Cancer Research, The Institute of Cancer Research, London, UK.

Csilla I Szabo (CI)

National Human Genome Research Institute, National Cancer Institute, Bethesda, MD, USA.

Rulla M Tamimi (RM)

Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

William J Tapper (WJ)

Faculty of Medicine, University of Southampton, Southampton, UK.

Jack A Taylor (JA)

Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Durham, NC, USA.
Epigenetic and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Durham, NC, USA.

Manuel R Teixeira (MR)

Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.
Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal.
ORCID: 0000-0002-4896-5982

MaryBeth Terry (M)

Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.

Mads Thomassen (M)

Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.

Darcy L Thull (DL)

Department of Medicine, Magee-Womens Hospital, School of Medicine, University of Pittsburgh , Pittsburgh, PA, USA.

Marc Tischkowitz (M)

Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montréal, Québec, Canada.
Department of Medical Genetics, National Institute for Health Research, Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK.

Amanda E Toland (AE)

Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, USA.
ORCID: 0000-0002-0271-1792

Rob A E M Tollenaar (RAEM)

Department of Surgery, Leiden University Medical Center, Leiden, the Netherlands.

Ian Tomlinson (I)

Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.
ORCID: 0000-0003-3037-1470

Diana Torres (D)

Molecular Genetics of Breast Cancer, DKFZ, Heidelberg, Germany.
Institute of Human Genetics, Pontificia Universidad Javeriana, Bogota, Colombia.

Melissa A Troester (MA)

Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Thérèse Truong (T)

Cancer and Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University of Paris-Saclay, Paris, France.

Nadine Tung (N)

Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA, USA.

Michael Untch (M)

Department of Gynecology and Obstetrics, Helios Clinics Berlin-Buch, Berlin, Germany.

Celine M Vachon (CM)

Department of Health Science Research, Division of Epidemiology, Mayo Clinic, Rochester, MN, USA.

Ans M W van den Ouweland (AMW)

Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands.

Lizet E van der Kolk (LE)

Family Cancer Clinic, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.

Elke M van Veen (EM)

Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester NIHR Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Division of Evolution and Genomic Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
ORCID: 0000-0001-8618-2332

Elizabeth J vanRensburg (EJ)

Department of Genetics, University of Pretoria, Pretoria, South Africa.
ORCID: 0000-0003-2077-230X

Ana Vega (A)

Molecular Medicine Unit, Fundación Pública Galega de Medicina Xenómica, Santiago de Compostela, Spain.
Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, Servicio Galego de Saude (SERGAS), Santiago de Compostela, Spain.
CIBERER, Santiago de Compostela, Spain.

Barbara Wappenschmidt (B)

Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.

Clarice R Weinberg (CR)

Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, NIH, Durham, NC, USA.

Jeffrey N Weitzel (JN)

Clinical Cancer Genomics, City of Hope, Duarte, CA, USA.
ORCID: 0000-0001-6714-092X

Hans Wildiers (H)

Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium.

Robert Winqvist (R)

Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland.
Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, Finland.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.
ORCID: 0000-0003-0932-9104

Alicja Wolk (A)

Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, Poland.
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
ORCID: 0000-0001-7387-6845

Xiaohong R Yang (XR)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services, Bethesda, MD, USA.

Drakoulis Yannoukakos (D)

Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece.
ORCID: 0000-0001-7509-3510

Wei Zheng (W)

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.
ORCID: 0000-0003-1226-070X

Kristin K Zorn (KK)

Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Roger L Milne (RL)

Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.
Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.
Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Victoria, Australia.
ORCID: 0000-0001-5764-7268

Peter Kraft (P)

Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
ORCID: 0000-0002-4472-8103

Jacques Simard (J)

Genomics Center, Centre Hospitalier Universitaire de Québec-Université Laval Research Center, Québec City, Québec, Canada.
ORCID: 0000-0001-6906-3390

Paul D P Pharoah (PDP)

Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
ORCID: 0000-0001-8494-732X

Kyriaki Michailidou (K)

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Biostatistics Unit, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.
Cyprus School of Molecular Medicine, Nicosia, Cyprus.
ORCID: 0000-0001-7065-1237

Antonis C Antoniou (AC)

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

Marjanka K Schmidt (MK)

Division of Molecular Pathology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.
Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.
ORCID: 0000-0002-2228-429X

Georgia Chenevix-Trench (G)

Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.

Douglas F Easton (DF)

Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
ORCID: 0000-0003-2444-3247

Nilanjan Chatterjee (N)

Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. nchatte2@jhu.edu.
Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. nchatte2@jhu.edu.
ORCID: 0000-0002-9060-008X

Montserrat García-Closas (M)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services, Bethesda, MD, USA.
ORCID: 0000-0003-1033-2650

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Protéine BRCA1 › Genome-wide association study identifies 32...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Maladies du sein › Tumeurs du sein › Genome-wide association study identifies 32...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études cas-témoins › Genome-wide association study identifies 32...
questionsmedicales.fr › Phénomènes génétiques › Génotype › Prédisposition génétique à une maladie › Genome-wide association study identifies 32...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Épidémiologie moléculaire › Étude d'association pangénomique › Genome-wide association study identifies 32...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Genome-wide association study identifies 32...
questionsmedicales.fr › Phénomènes génétiques › Liaison génétique › Déséquilibre de liaison › Genome-wide association study identifies 32...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Genome-wide association study identifies 32...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Maladies du sein › Tumeurs du sein › Tumeurs du sein triple-négatives › Genome-wide association study identifies 32...