"Hairy Cell Leukemia (HCL): 'Real World' Outcome".
Hairy cell leukemia
Outcome
Survival
Journal
Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion
ISSN: 0971-4502
Titre abrégé: Indian J Hematol Blood Transfus
Pays: India
ID NLM: 9425818
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
02
10
2018
accepted:
17
12
2018
entrez:
20
5
2020
pubmed:
20
5
2020
medline:
20
5
2020
Statut:
ppublish
Résumé
HCL is an uncommon B cell lympho-proliferative disorder with high remission rates. There is paucity of data on the long-term outcome of HCL from India. We retrospectively collected data from individual case records of patients with HCL who were treated in Cancer Institute, Chennai from January 2001 until January 2018. Sixteen patients were diagnosed with HCL and were treated with cladribine (81%), interferon (13%) and one patient received only best supportive care (6%). All the treated patients achieved complete response. More than half of the patients developed febrile neutropenia but there were no treatment related mortality. The 5-year DFS was 77% and 5-year OS was 80%. Relapse of disease was seen in 27%. HCL is a curable malignancy with high remission rates and survival comparable to patient treated in west.
Identifiants
pubmed: 32425376
doi: 10.1007/s12288-019-01199-2
pii: 1199
pmc: PMC7229049
doi:
Types de publication
Journal Article
Langues
eng
Pagination
267-270Informations de copyright
© Indian Society of Hematology and Blood Transfusion 2019.
Déclaration de conflit d'intérêts
Conflict of interestThe authors declare that they have no conflict of interest.
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