Endothelial-to-Mesenchymal Transition in Calcific Aortic Valve Disease.
Calcific aortic valve disease
Endothelial-to-mesenchymal transition
Regulatory network
Valvular endothelial cell
Journal
Acta Cardiologica Sinica
ISSN: 1011-6842
Titre abrégé: Acta Cardiol Sin
Pays: China (Republic : 1949- )
ID NLM: 101687085
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
entrez:
20
5
2020
pubmed:
20
5
2020
medline:
20
5
2020
Statut:
ppublish
Résumé
Calcific aortic valve disease (CAVD) represents a significant threat to cardiovascular health worldwide, and the incidence of this sclerocalcific valve disease has rapidly increased along with a rise in life expectancy. Compelling evidence has suggested that CAVD is an actively and finely regulated pathophysiological process even though it has been referred to as "degenerative" for decades. A striking similarity has been noted in the etiopathogenesis between CAVD and atherosclerosis, a classical proliferative sclerotic vascular disease.
Identifiants
pubmed: 32425433
doi: 10.6515/ACS.202005_36(3).20200213A
pmc: PMC7220963
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
183-194Références
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