Efficacy of WINROP as a Screening Tool for Retinopathy of Prematurity in the East Coast of Malaysia.
WINROP
retinopathy of prematurity
sensitivity
specificity
Journal
Clinical ophthalmology (Auckland, N.Z.)
ISSN: 1177-5467
Titre abrégé: Clin Ophthalmol
Pays: New Zealand
ID NLM: 101321512
Informations de publication
Date de publication:
2020
2020
Historique:
received:
31
01
2020
accepted:
06
04
2020
entrez:
20
5
2020
pubmed:
20
5
2020
medline:
20
5
2020
Statut:
epublish
Résumé
To evaluate the efficacy of the "weight, insulin-like growth factor 1, neonatal retinopathy of prematurity" (WINROP) algorithm in predicting retinopathy of prematurity (ROP) requiring treatment in Malaysia. This was a retrospective study involving premature infants with gestational age less than 32 weeks treated from September 2016 to March 2019 in Hospital Universiti Sains Malaysia. Clinical diagnosis was made based on Early Treatment Retinopathy of Prematurity study. Participants' weekly weight gain since birth was entered in the website (http://winrop.com), along with date of birth, gestational age and final clinical examination outcome. WINROP software signals an alarm if an infant is at high risk of developing ROP requiring treatment during weight data entry. By using the alarm status, the sensitivity and specificity of this algorithm for predicting ROP requiring treatment were obtained. Ninety-two infants were included in this study. An alarm was detected in 67 infants (72.8%). There were a total of 53 infants (54.6%) with no ROP, 15 (16.3%) of whom developed stage 1 ROP, 10 (10.8%) who developed stage 2 ROP and 14 infants (15.2%) who developed stage 3 ROP. In our study, WINROP sensitivity was 95.2% and specificity was 33.8%. WINROP is recommended as an initial screening tool for premature infants at risk of developing treatment-requiring ROP in Malaysia. It may help to alert clinicians managing severely ill infants when clinical examinations are less possible.
Identifiants
pubmed: 32425496
doi: 10.2147/OPTH.S247820
pii: 247820
pmc: PMC7188201
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1101-1106Informations de copyright
© 2020 Lim et al.
Déclaration de conflit d'intérêts
The authors report no funding and no conflicts of interest for this work.
Références
Arch Ophthalmol. 2012 Aug;130(8):992-9
pubmed: 22491391
Indian J Ophthalmol. 2018 Jan;66(1):110-113
pubmed: 29283134
Adv Neonatal Care. 2011 Aug;11(4):291-7
pubmed: 22123352
Pediatrics. 2009 Apr;123(4):e638-45
pubmed: 19289449
Arch Ophthalmol. 2005 Jul;123(7):991-9
pubmed: 16009843
Trans Am Ophthalmol Soc. 2004;102:233-48; discussion 248-50
pubmed: 15747762
Middle East Afr J Ophthalmol. 2012 Jul-Sep;19(3):289-94
pubmed: 22837621
Arch Ophthalmol. 2012 Jun;130(6):720-3
pubmed: 22801831
PLoS One. 2013 Sep 12;8(9):e73256
pubmed: 24069180
Jpn J Ophthalmol. 2020 Mar;64(2):223-227
pubmed: 31900868
Eye (Lond). 2020 Apr;34(4):607-608
pubmed: 31582794
J AAPOS. 2017 Jun;21(3):229-233
pubmed: 28506724
Eye Brain. 2016 May 19;8:31-36
pubmed: 28539799
Dev Period Med. 2017;21(4):336-343
pubmed: 29291361
Am J Perinatol. 2015 Feb;30(2):149-54
pubmed: 24915558
Biol Neonate. 2004;86(3):195-200
pubmed: 15240989
Arch Ophthalmol. 2010 Nov;128(11):1432-6
pubmed: 21060045
Neonatology. 2013;104(2):127-32
pubmed: 23887600
Br J Ophthalmol. 2014 Jul;98(7):964-6
pubmed: 24568873
JAMA Ophthalmol. 2013 Jan;131(1):62-6
pubmed: 23307210
Arch Dis Child Fetal Neonatal Ed. 2014 Jan;99(1):F29-33
pubmed: 23985883
J AAPOS. 2016 Dec;20(6):486-489
pubmed: 27810424
Arch Ophthalmol. 2010 Apr;128(4):443-7
pubmed: 20385939