Suitability evaluation on material specifications and edible methods of Dendrobii Officinalis Caulis based on holistic polysaccharide marker.
Commercial specification
Dendrobii Officinalis Caulis
Edible extraction methods
Holistic polysaccharide marker (HPM)
Immunomodulatory activity
Journal
Chinese medicine
ISSN: 1749-8546
Titre abrégé: Chin Med
Pays: England
ID NLM: 101265109
Informations de publication
Date de publication:
2020
2020
Historique:
received:
14
11
2019
accepted:
05
02
2020
entrez:
20
5
2020
pubmed:
20
5
2020
medline:
20
5
2020
Statut:
epublish
Résumé
Dendrobii Officinalis Caulis (DC) is a well-known tonic herbal medicine worldwide and has favorable immunomodulatory activity. Various material specifications of DC are available in herbal markets, and DC is ingested by different edible methods. However, whether these specifications and edible methods are suitable or not remains unknown. In this study, we evaluated the suitability of four material specifications (fresh stem, dried stem, The results showed that the HPMs were found to be quantitatively different from various specification of DC and edible methods. In vivo analysis indicated that the HPMs exerted positive effects on innate immune responses by increment in proliferation of splenocytes, secretion of IL-2 and cytotoxicity activity of NK cells. Moreover, the dosage amount of HPM should be defined as a certain range, but not the larger the better, for exerting strong immunological activities. According to the both chemical and biological results,
Sections du résumé
BACKGROUND
BACKGROUND
Dendrobii Officinalis Caulis (DC) is a well-known tonic herbal medicine worldwide and has favorable immunomodulatory activity. Various material specifications of DC are available in herbal markets, and DC is ingested by different edible methods. However, whether these specifications and edible methods are suitable or not remains unknown.
METHODS
METHODS
In this study, we evaluated the suitability of four material specifications (fresh stem, dried stem,
RESULTS
RESULTS
The results showed that the HPMs were found to be quantitatively different from various specification of DC and edible methods. In vivo analysis indicated that the HPMs exerted positive effects on innate immune responses by increment in proliferation of splenocytes, secretion of IL-2 and cytotoxicity activity of NK cells. Moreover, the dosage amount of HPM should be defined as a certain range, but not the larger the better, for exerting strong immunological activities.
CONCLUSION
CONCLUSIONS
According to the both chemical and biological results,
Identifiants
pubmed: 32426031
doi: 10.1186/s13020-020-0300-7
pii: 300
pmc: PMC7218507
doi:
Types de publication
Journal Article
Langues
eng
Pagination
46Informations de copyright
© The Author(s) 2020.
Déclaration de conflit d'intérêts
Competing interestsThe authors declare that they have no competing interests.
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