Hemoglobin Levels and Red Blood Cells Distribution Width Highlights Glioblastoma Patients Subgroup With Improved Median Overall Survival.

RDW (red cell distribution width) glioblastoma multiforme (GBM) hemoglobin overall survival prognostic factors

Journal

Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867

Informations de publication

Date de publication:
2020
Historique:
received: 11 12 2019
accepted: 11 03 2020
entrez: 20 5 2020
pubmed: 20 5 2020
medline: 20 5 2020
Statut: epublish

Résumé

Glioblastoma multiforme (GBM) is known for its dismal prognosis, though its dependence on patients' readily available RBCs parameters is not fully established. In this work, 170 GBM patients, diagnosed and treated in Soroka University Medical Center (SUMC) over the last 12 years were retrospectively inspected for their survival dependency on pre-operative RBCs parameters. Besides KPS and tumor resection supplemented by oncological treatment, age under 70 (HR = 0.4, 95% CI 0.24-0.65,

Identifiants

pubmed: 32426265
doi: 10.3389/fonc.2020.00432
pmc: PMC7212453
doi:

Types de publication

Journal Article

Langues

eng

Pagination

432

Informations de copyright

Copyright © 2020 Kaisman-Elbaz, Elbaz, Merkin, Dym, Noy, Atar-Vardi, Bari, Turiel, Alt, Zamed, Eskira, Lavrenkov, Kezerle, Dyomin and Melamed.

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Auteurs

Tehila Kaisman-Elbaz (T)

Department of Neurosurgery, Soroka University Medical Center, Be'er Sheva, Israel.
Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.

Yonatan Elbaz (Y)

Physics Department, Nuclear Research Center - Negev, Be'er Sheva, Israel.

Vladimir Merkin (V)

Department of Neurosurgery, Soroka University Medical Center, Be'er Sheva, Israel.
Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.

Lianne Dym (L)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.

Ariel Noy (A)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.

Maya Atar-Vardi (M)

Clinical Research Center, Soroka University Medical Center, Be'er Sheva, Israel.

Romi Bari (R)

Clinical Research Center, Soroka University Medical Center, Be'er Sheva, Israel.

Sivan Turiel (S)

Clinical Research Center, Soroka University Medical Center, Be'er Sheva, Israel.

Adi Alt (A)

Department of Neurosurgery, Soroka University Medical Center, Be'er Sheva, Israel.

Tali Zamed (T)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.

Yael Eskira (Y)

Department of Neurosurgery, Soroka University Medical Center, Be'er Sheva, Israel.
Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.

Konstantin Lavrenkov (K)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.
Institute of Oncology, Soroka University Medical Center, Be'er Sheva, Israel.

Yarden Kezerle (Y)

Institute of Pathology, Soroka University Medical Center, Be'er Sheva, Israel.

Victor Dyomin (V)

Institute of Pathology, Soroka University Medical Center, Be'er Sheva, Israel.

Israel Melamed (I)

Department of Neurosurgery, Soroka University Medical Center, Be'er Sheva, Israel.
Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.

Classifications MeSH