Radiological pseudoprogression post-radiotherapy in a child with pineal germ cell tumour.
germ cell tumour
germinoma
intracranial
paediatric
pineal
pseudoprogression
teratoma
Journal
Pediatric blood & cancer
ISSN: 1545-5017
Titre abrégé: Pediatr Blood Cancer
Pays: United States
ID NLM: 101186624
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
received:
18
01
2020
revised:
02
04
2020
accepted:
26
04
2020
pubmed:
20
5
2020
medline:
25
8
2020
entrez:
20
5
2020
Statut:
ppublish
Résumé
Little is known about pseudoprogression in brain tumours other than gliomas. A 9-year-old male child with a pineal teratoma/germinoma underwent surgical resection followed by adjuvant chemo-radiotherapy. The magnetic resonance imaging scan 4 months post-radiotherapy showed a contrast-enhancing lesion within the surgical cavity suspicious of recurrence. These radiological findings subsequently resolved without any specific intervention. The child continues in remission 2 years post-treatment. This case illustrates the occurrence of pseudoprogression post-radiotherapy in intracranial GCT and highlights an unmet need for greater implementation of functional imaging techniques in paediatric neuro-oncology to avoid undue discontinuation of effective treatments or inappropriate enrolment in clinical trials.
Types de publication
Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e28407Informations de copyright
© 2020 The Authors. Pediatric Blood & Cancer published by Wiley Periodicals, Inc.
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