Donor-to-recipient transmission and reactivation in a kidney transplant recipient of an inherited chromosomally integrated HHV-6A: Evidence and outcomes.
clinical research/practice
infection and infectious agents - viral: human herpesvirus 6 (HHV-6)
infectious disease
kidney disease: infectious
kidney transplantation/nephrology
translational research/science
Journal
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
ISSN: 1600-6143
Titre abrégé: Am J Transplant
Pays: United States
ID NLM: 100968638
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
received:
02
04
2020
revised:
04
05
2020
accepted:
07
05
2020
pubmed:
20
5
2020
medline:
22
6
2021
entrez:
20
5
2020
Statut:
ppublish
Résumé
Human herpesvirus (HHV)-6A can be inherited and chromosomally integrated (iciHHV-6A), and donor-to-recipient transmission has been reported in solid organ transplant. However, when HHV-6A reactivation happens after transplant, the source of HHV-6A is often not evident and its pathogenicity remains unclear. Here, we present an exhaustive case of donor-to-recipient transmission and reactivation of iciHHV-6A through kidney transplant. The absence of HHV-6A genome from the nails of the recipient excluded a recipient-related iciHHV-6A. Viral loads > 7 log
Identifiants
pubmed: 32428994
doi: 10.1111/ajt.16067
pii: S1600-6135(22)21649-9
doi:
Substances chimiques
DNA, Viral
0
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
3667-3672Informations de copyright
© 2020 The American Society of Transplantation and the American Society of Transplant Surgeons.
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