TNFα Rescues Dendritic Cell Development in Hematopoietic Stem and Progenitor Cells Lacking C/EBPα.


Journal

Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052

Informations de publication

Date de publication:
15 05 2020
Historique:
received: 13 02 2020
revised: 04 05 2020
accepted: 14 05 2020
entrez: 21 5 2020
pubmed: 21 5 2020
medline: 25 2 2021
Statut: epublish

Résumé

Dendritic cells (DCs) are crucial effectors of the immune system, which are formed from hematopoietic stem and progenitor cells (HSPCs) by a multistep process regulated by cytokines and distinct transcriptional mechanisms. C/EBPα is an important myeloid transcription factor, but its role in DC formation is not well defined. Using a

Identifiants

pubmed: 32429067
pii: cells9051223
doi: 10.3390/cells9051223
pmc: PMC7291045
pii:
doi:

Substances chimiques

CCAAT-Enhancer-Binding Protein-alpha 0
Chemokines 0
Membrane Proteins 0
Tumor Necrosis Factor-alpha 0
flt3 ligand protein 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Références

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Auteurs

Subramanian Anirudh (S)

Division of Hematology, Medical University of Graz, Auenbruggerplatz 38, A-8036 Graz, Austria.

Angelika Rosenberger (A)

Division of Hematology, Medical University of Graz, Auenbruggerplatz 38, A-8036 Graz, Austria.

Elke Schwarzenberger (E)

Division of Immunology and Pathophysiology, Otto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Medical University of Graz, Heinrichstraße 31, A-8010 Graz, Austria.

Carolin Schaefer (C)

Division of Hematology, Medical University of Graz, Auenbruggerplatz 38, A-8036 Graz, Austria.

Herbert Strobl (H)

Division of Immunology and Pathophysiology, Otto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Medical University of Graz, Heinrichstraße 31, A-8010 Graz, Austria.

Armin Zebisch (A)

Division of Hematology, Medical University of Graz, Auenbruggerplatz 38, A-8036 Graz, Austria.
Division of Pharmacology, Otto-Loewi-Research Center for Vascular Biology, Immunology and Inflammation, Medical University of Graz, Universitätsplatz 4, A-8010 Graz, Austria.

Heinz Sill (H)

Division of Hematology, Medical University of Graz, Auenbruggerplatz 38, A-8036 Graz, Austria.

Albert Wölfler (A)

Division of Hematology, Medical University of Graz, Auenbruggerplatz 38, A-8036 Graz, Austria.

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Classifications MeSH