Vitamin D and Cardiovascular Risk: which Implications in Children?
cardiovascular risk
childhood
extra-skeletal effects
vitamin D
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
16 May 2020
16 May 2020
Historique:
received:
29
04
2020
revised:
12
05
2020
accepted:
14
05
2020
entrez:
21
5
2020
pubmed:
21
5
2020
medline:
13
2
2021
Statut:
epublish
Résumé
Vitamin D (25OHD) pleiotropic effects are widely recognized and studied. Recently, vitamin D cardiovascular effects are gaining interest, especially in children, although the studies present conflicting data. Some randomized controlled trials (RCTs) have demonstrated that cardiovascular risk markers, such as lipid parameters, inflammation markers, blood pressure, and arterial stiffness, are unaffected by vitamin D supplementation. By contrast, other studies show that low vitamin D levels are associated with higher risk of cardiovascular disease (CVD) and mortality, and support that increased risk of these diseases occurs primarily in people with vitamin D deficiency. An update on these points in pediatric patients is certainly of interest to focus on possible benefits of its supplementation.
Identifiants
pubmed: 32429489
pii: ijms21103536
doi: 10.3390/ijms21103536
pmc: PMC7279000
pii:
doi:
Substances chimiques
Vitamin D
1406-16-2
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
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