Toxoplasma gondii in the Eurasian kestrel (Falco tinnunculus) in northern Italy.


Journal

Parasites & vectors
ISSN: 1756-3305
Titre abrégé: Parasit Vectors
Pays: England
ID NLM: 101462774

Informations de publication

Date de publication:
19 May 2020
Historique:
received: 20 02 2020
accepted: 12 05 2020
entrez: 21 5 2020
pubmed: 21 5 2020
medline: 30 1 2021
Statut: epublish

Résumé

Identifying factors that sustain parasite transmission is important for understanding their spread and emergence, including how changes in biodiversity may affect parasite prevalence and spread. Toxoplasma gondii is a protozoan parasite infecting humans and animals. Birds can acquire T. gondii infection through ingestion either of oocysts from the ground or of tissue cysts present in infected prey and are therefore suitable indicators of the presence of T. gondii in the natural environment. The aim of the study included the evaluation of T. gondii seroprevalence in clinically healthy Eurasian kestrels (Falco tinnunculus) using a modified agglutination test. Birds were captured in a small area of Parma (northern Italy) for two consecutive years (2016-2017), sex and age determined and serological study carried out. Food sources for the birds were also evaluated, in particular rodent and grasshopper population estimates in the study area. The biomass of rodents and grasshoppers per hectare was estimated in order to directly compare food availability. Statistical analyses were performed in order to evaluate factors influencing the probability of kestrels being T. gondii-seropositive using R 3.4.4 fitting linear mixed-effect models with the 'glmer' function of the package lme4, 'lsmean' in package lsmean for pair-wise post-hoc comparisons using differences of least square means (DLSM) and the 'betareg' function of the package betareg for beta regression. Seroprevalence for T. gondii was 33.3% (49/147) in 2016, while in 2017 seroprevalence decreased to 14.3% (13/91). An increase in the probability of kestrels being T. gondii-seropositive was associated with a higher rodent biomass in the environment, suggesting a positive feedback of the biotic factors driving infection risk. These results underline the need for multidisciplinary studies aimed at better understanding pathogen-host relationships and for predictions in disease ecology.

Sections du résumé

BACKGROUND BACKGROUND
Identifying factors that sustain parasite transmission is important for understanding their spread and emergence, including how changes in biodiversity may affect parasite prevalence and spread. Toxoplasma gondii is a protozoan parasite infecting humans and animals. Birds can acquire T. gondii infection through ingestion either of oocysts from the ground or of tissue cysts present in infected prey and are therefore suitable indicators of the presence of T. gondii in the natural environment.
METHODS METHODS
The aim of the study included the evaluation of T. gondii seroprevalence in clinically healthy Eurasian kestrels (Falco tinnunculus) using a modified agglutination test. Birds were captured in a small area of Parma (northern Italy) for two consecutive years (2016-2017), sex and age determined and serological study carried out. Food sources for the birds were also evaluated, in particular rodent and grasshopper population estimates in the study area. The biomass of rodents and grasshoppers per hectare was estimated in order to directly compare food availability. Statistical analyses were performed in order to evaluate factors influencing the probability of kestrels being T. gondii-seropositive using R 3.4.4 fitting linear mixed-effect models with the 'glmer' function of the package lme4, 'lsmean' in package lsmean for pair-wise post-hoc comparisons using differences of least square means (DLSM) and the 'betareg' function of the package betareg for beta regression.
RESULTS RESULTS
Seroprevalence for T. gondii was 33.3% (49/147) in 2016, while in 2017 seroprevalence decreased to 14.3% (13/91). An increase in the probability of kestrels being T. gondii-seropositive was associated with a higher rodent biomass in the environment, suggesting a positive feedback of the biotic factors driving infection risk.
CONCLUSIONS CONCLUSIONS
These results underline the need for multidisciplinary studies aimed at better understanding pathogen-host relationships and for predictions in disease ecology.

Identifiants

pubmed: 32429990
doi: 10.1186/s13071-020-04134-x
pii: 10.1186/s13071-020-04134-x
pmc: PMC7236205
doi:

Substances chimiques

Antibodies, Protozoan 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

262

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Auteurs

Tiziano Iemmi (T)

Department of Veterinary Science, University of Parma, Parma, Italy.
URCA (Unione Regionale Cacciatori dell'Appennino), Parma, Italy.

Alice Vismarra (A)

Department of Veterinary Science, University of Parma, Parma, Italy.

Carlo Mangia (C)

Department of Veterinary Science, University of Parma, Parma, Italy.

Rolando Zanin (R)

URCA (Unione Regionale Cacciatori dell'Appennino), Parma, Italy.

Marco Genchi (M)

Department of Veterinary Science, University of Parma, Parma, Italy.

Paolo Lanfranchi (P)

Department of Veterinary Medicine, Università degli Studi di Milano, Milan, Italy.

Laura Helen Kramer (LH)

Department of Veterinary Science, University of Parma, Parma, Italy. kramerlh@unipr.it.

Nicoletta Formenti (N)

Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini", via Bianchi 7/9, 25124, Brescia, Italy.

Nicola Ferrari (N)

Department of Veterinary Medicine, Università degli Studi di Milano, Milan, Italy.
Centro di Ricerca Coordinata Epidemiologia e Sorveglianza Molecolare delle Infezioni, EpiSoMI, Università degli Studi di Milano, Milan, Italy.

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Classifications MeSH