Facile Strategy on Hydrophilic Modification of Poly(ε-caprolactone) Scaffolds for Assisting Tissue-Engineered Meniscus Constructs

fused deposition modeling hydrophilic modification poly(ε-caprolactone) regenerative medicine scaffold three-dimension printing tissue-engineered meniscus

Journal

Frontiers in pharmacology
ISSN: 1663-9812
Titre abrégé: Front Pharmacol
Pays: Switzerland
ID NLM: 101548923

Informations de publication

Date de publication:
2020
Historique:
received: 26 10 2019
accepted: 25 03 2020
entrez: 21 5 2020
pubmed: 21 5 2020
medline: 21 5 2020
Statut: epublish

Résumé

Poly(ε-caprolactone) (PCL) derived scaffolds have been extensively explored in the field of tissue-engineered meniscus (TEM) originating from their good biosafety and biomechanical properties. However, the poor intrinsic hydrophobicity severely hindered their wide applications for the scaffold-assisted tissue regeneration. Herein, we developed a simple strategy on surface modification of three-dimensional (3D) PCL scaffolds

Identifiants

pubmed: 32431606
doi: 10.3389/fphar.2020.00471
pmc: PMC7216581
doi:

Types de publication

Journal Article

Langues

eng

Pagination

471

Informations de copyright

Copyright © 2020 Zhou, Chen, Zhang, Jiang, Yuan, Mao, Yang, Jiang, Wang and Yu.

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Auteurs

Zhu-Xing Zhou (ZX)

Knee Surgery Department of the Institute of Sports Medicine, Peking University Third Hospital, Beijing, China.

You-Rong Chen (YR)

Knee Surgery Department of the Institute of Sports Medicine, Peking University Third Hospital, Beijing, China.

Ji-Ying Zhang (JY)

Knee Surgery Department of the Institute of Sports Medicine, Peking University Third Hospital, Beijing, China.

Dong Jiang (D)

Knee Surgery Department of the Institute of Sports Medicine, Peking University Third Hospital, Beijing, China.

Fu-Zhen Yuan (FZ)

Knee Surgery Department of the Institute of Sports Medicine, Peking University Third Hospital, Beijing, China.

Zi-Mu Mao (ZM)

Knee Surgery Department of the Institute of Sports Medicine, Peking University Third Hospital, Beijing, China.

Fei Yang (F)

Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics & Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
University of Chinese Academy of Sciences, Beijing, China.

Wen-Bo Jiang (WB)

Clinical Translational R&D Center of 3D Printing Technology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Xing Wang (X)

Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics & Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
University of Chinese Academy of Sciences, Beijing, China.

Jia-Kuo Yu (JK)

Knee Surgery Department of the Institute of Sports Medicine, Peking University Third Hospital, Beijing, China.

Classifications MeSH