Statin therapy is associated with lower prevalence of gut microbiota dysbiosis.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
05 2020
Historique:
received: 05 08 2019
accepted: 03 04 2020
pubmed: 21 5 2020
medline: 1 7 2020
entrez: 21 5 2020
Statut: ppublish

Résumé

Microbiome community typing analyses have recently identified the Bacteroides2 (Bact2) enterotype, an intestinal microbiota configuration that is associated with systemic inflammation and has a high prevalence in loose stools in humans

Identifiants

pubmed: 32433607
doi: 10.1038/s41586-020-2269-x
pii: 10.1038/s41586-020-2269-x
doi:

Substances chimiques

Hydroxymethylglutaryl-CoA Reductase Inhibitors 0

Types de publication

Journal Article Observational Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

310-315

Investigateurs

Renato Alves (R)
Chloe Amouyal (C)
Ehm Astrid Andersson Galijatovic (EAA)
Olivier Barthelemy (O)
Jean-Paul Batisse (JP)
Magalie Berland (M)
Randa Bittar (R)
Hervé Blottière (H)
Frederic Bosquet (F)
Rachid Boubrit (R)
Olivier Bourron (O)
Mickael Camus (M)
Dominique Cassuto (D)
Cecile Ciangura (C)
Jean-Philippe Collet (JP)
Maria-Carlota Dao (MC)
Jean Debedat (J)
Morad Djebbar (M)
Angélique Doré (A)
Line Engelbrechtsen (L)
Soraya Fellahi (S)
Sebastien Fromentin (S)
Philippe Giral (P)
Marianne Graine (M)
Agnes Hartemann (A)
Bolette Hartmann (B)
Gerard Helft (G)
Serge Hercberg (S)
Malene Hornbak (M)
Richard Isnard (R)
Sophie Jaqueminet (S)
Niklas Rye Jørgensen (NR)
Hanna Julienne (H)
Johanne Justesen (J)
Judith Kammer (J)
Mathieu Kerneis (M)
Jean Khemis (J)
Nikolaj Krarup (N)
Michael Kuhn (M)
Aurélie Lampuré (A)
Véronique Lejard (V)
Florence Levenez (F)
Lea Lucas-Martini (L)
Robin Massey (R)
Nicolas Maziers (N)
Jonathan Medina-Stamminger (J)
Lucas Moitinho-Silva (L)
Gilles Montalescot (G)
Sandrine Moutel (S)
Laetitia Pasero Le Pavin (LP)
Christine Poitou-Bernert (C)
Francoise Pousset (F)
Laurence Pouzoulet (L)
Sebastian Schmidt (S)
Johanne Silvain (J)
Mathilde Svendstrup (M)
Timothy Swartz (T)
Thierry Vanduyvenboden (T)
Camille Vatier (C)
Eric Verger (E)
Stefanie Walther (S)

Commentaires et corrections

Type : CommentIn
Type : CommentIn
Type : CommentIn

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Auteurs

Sara Vieira-Silva (S)

Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.
Center for Microbiology, VIB, Leuven, Belgium.

Gwen Falony (G)

Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.
Center for Microbiology, VIB, Leuven, Belgium.

Eugeni Belda (E)

Nutrition and Obesities: Systemic Approaches Research Unit (NutriOmics), INSERM, Sorbonne Université, Paris, France.
Institute of Cardiometabolism and Nutrition, Integromics Unit, Paris, France.

Trine Nielsen (T)

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Judith Aron-Wisnewsky (J)

Nutrition and Obesities: Systemic Approaches Research Unit (NutriOmics), INSERM, Sorbonne Université, Paris, France.
Nutrition Department, Pitie-Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris, Paris, France.

Rima Chakaroun (R)

Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.

Sofia K Forslund (SK)

Experimental and Clinical Research Center, Charité-Universitätsmedizin and Max-Delbrück Center, Berlin, Germany.
Structural and Computational Biology, European Molecular Biology Laboratory, Heidelberg, Germany.
Max Delbruck Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany.

Karen Assmann (K)

Nutrition and Obesities: Systemic Approaches Research Unit (NutriOmics), INSERM, Sorbonne Université, Paris, France.

Mireia Valles-Colomer (M)

Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.
Center for Microbiology, VIB, Leuven, Belgium.

Thi Thuy Duyen Nguyen (TTD)

Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.
Center for Microbiology, VIB, Leuven, Belgium.

Sebastian Proost (S)

Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.
Center for Microbiology, VIB, Leuven, Belgium.

Edi Prifti (E)

Nutrition and Obesities: Systemic Approaches Research Unit (NutriOmics), INSERM, Sorbonne Université, Paris, France.
Institute of Cardiometabolism and Nutrition, Integromics Unit, Paris, France.
Unité de Modélisation Mathématique et Informatique des Systèmes Complexes, UMMISCO, Sorbonne Université, IRD, Bondy, France.

Valentina Tremaroli (V)

Wallenberg Laboratory, Department of Molecular and Clinical Medicine and Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Nicolas Pons (N)

Université Paris-Saclay, INRAE, Metagenopolis, Jouy en Josas, France.

Emmanuelle Le Chatelier (E)

Université Paris-Saclay, INRAE, Metagenopolis, Jouy en Josas, France.

Fabrizio Andreelli (F)

Nutrition and Obesities: Systemic Approaches Research Unit (NutriOmics), INSERM, Sorbonne Université, Paris, France.
Diabetes Department, Pitie-Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris, Paris, France.

Jean-Phillippe Bastard (JP)

UF Biomarqueurs Inflammatoires et Métaboliques, Biochemistry and Hormonology Department, Tenon Hospital, Assistance Publique Hôpitaux de Paris, Paris, France.
Centre de Recherche Saint-Antoine, Sorbonne Université-INSERM UMR-S 938, IHU ICAN, Paris, France.

Luis Pedro Coelho (LP)

Structural and Computational Biology, European Molecular Biology Laboratory, Heidelberg, Germany.
Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China.

Nathalie Galleron (N)

Université Paris-Saclay, INRAE, Metagenopolis, Jouy en Josas, France.

Tue H Hansen (TH)

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Jean-Sébastien Hulot (JS)

NICO Cardio-oncology Program, CIC-1421, Department of Pharmacology, Pitié-Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris, INSERM, Sorbonne Université, Paris, France.
Université de Paris, PARCC, INSERM, Paris, France.
CIC1418 and DMU CARTE, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges-Pompidou, Paris, France.

Christian Lewinter (C)

Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

Helle K Pedersen (HK)

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Benoit Quinquis (B)

Université Paris-Saclay, INRAE, Metagenopolis, Jouy en Josas, France.

Christine Rouault (C)

Nutrition and Obesities: Systemic Approaches Research Unit (NutriOmics), INSERM, Sorbonne Université, Paris, France.

Hugo Roume (H)

Université Paris-Saclay, INRAE, Metagenopolis, Jouy en Josas, France.

Joe-Elie Salem (JE)

NICO Cardio-oncology Program, CIC-1421, Department of Pharmacology, Pitié-Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris, INSERM, Sorbonne Université, Paris, France.

Nadja B Søndertoft (NB)

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Sothea Touch (S)

Nutrition and Obesities: Systemic Approaches Research Unit (NutriOmics), INSERM, Sorbonne Université, Paris, France.

Marc-Emmanuel Dumas (ME)

Computational and Systems Medicine, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.
Genomic and Environmental Medicine, National Heart & Lung Institute, Faculty of Medicine, Imperial College London, London, UK.

Stanislav Dusko Ehrlich (SD)

Université Paris-Saclay, INRAE, Metagenopolis, Jouy en Josas, France.

Pilar Galan (P)

Sorbonne Paris Cité Epidemiology and Statistics Research Centre (CRESS), U1153 INSERM, U1125, INRA, CNAM, University of Paris, Nutritional Epidemiology Research Team (EREN), Bobigny, France.

Jens P Gøtze (JP)

Department of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

Torben Hansen (T)

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Jens J Holst (JJ)

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Lars Køber (L)

Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

Ivica Letunic (I)

Biobyte Solutions, Heidelberg, Germany.

Jens Nielsen (J)

Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.

Jean-Michel Oppert (JM)

Nutrition Department, Pitie-Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris, Paris, France.

Michael Stumvoll (M)

Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.
Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig, Leipzig, Germany.

Henrik Vestergaard (H)

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Jean-Daniel Zucker (JD)

Nutrition and Obesities: Systemic Approaches Research Unit (NutriOmics), INSERM, Sorbonne Université, Paris, France.
Institute of Cardiometabolism and Nutrition, Integromics Unit, Paris, France.
Unité de Modélisation Mathématique et Informatique des Systèmes Complexes, UMMISCO, Sorbonne Université, IRD, Bondy, France.

Peer Bork (P)

Structural and Computational Biology, European Molecular Biology Laboratory, Heidelberg, Germany.
Molecular Medicine Partnership Unit, University of Heidelberg and European Molecular Biology Laboratory, Heidelberg, Germany.
Department of Bioinformatics, Biocenter, University of Würzburg, Würzburg, Germany.

Oluf Pedersen (O)

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Fredrik Bäckhed (F)

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Wallenberg Laboratory, Department of Molecular and Clinical Medicine and Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Karine Clément (K)

Nutrition and Obesities: Systemic Approaches Research Unit (NutriOmics), INSERM, Sorbonne Université, Paris, France. karine.clement@inserm.fr.
Nutrition Department, Pitie-Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris, Paris, France. karine.clement@inserm.fr.

Jeroen Raes (J)

Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium. jeroen.raes@kuleuven.be.
Center for Microbiology, VIB, Leuven, Belgium. jeroen.raes@kuleuven.be.

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