Relationships Between Chemoreflex Responses, Sleep Quality, and Hematocrit in Andean Men and Women.
control of breathing
excessive erythrocytosis
high altitude
hypoxia
sleep
Journal
Frontiers in physiology
ISSN: 1664-042X
Titre abrégé: Front Physiol
Pays: Switzerland
ID NLM: 101549006
Informations de publication
Date de publication:
2020
2020
Historique:
received:
12
02
2020
accepted:
08
04
2020
entrez:
22
5
2020
pubmed:
22
5
2020
medline:
22
5
2020
Statut:
epublish
Résumé
Andean highlanders are challenged by chronic hypoxia and many exhibit elevated hematocrit (Hct) and blunted ventilation compared to other high-altitude populations. While many Andeans develop Chronic Mountain Sickness (CMS) and excessive erythrocytosis, Hct varies markedly within Andean men and women and may be driven by individual differences in ventilatory control and/or sleep events which exacerbate hypoxemia. To test this hypothesis, we quantified relationships between resting ventilation and ventilatory chemoreflexes, sleep desaturation, breathing disturbance, and Hct in Andean men and women. Ventilatory measures were made in 109 individuals (
Identifiants
pubmed: 32435207
doi: 10.3389/fphys.2020.00437
pmc: PMC7219107
doi:
Types de publication
Journal Article
Langues
eng
Pagination
437Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL145470
Pays : United States
Organisme : NHLBI NIH HHS
ID : R21 HL121794
Pays : United States
Organisme : NHLBI NIH HHS
ID : F32 HL131218
Pays : United States
Organisme : NHLBI NIH HHS
ID : K24 HL132105
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL119201
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL085188
Pays : United States
Organisme : NHLBI NIH HHS
ID : F32 HL131306
Pays : United States
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : NHLBI NIH HHS
ID : T32 HL134632
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL081823
Pays : United States
Informations de copyright
Copyright © 2020 Heinrich, Orr, Gilbertson, Anza-Ramirez, DeYoung, Djokic, Corante, Vizcardo-Galindo, Macarlupu, Gaio, Powell, Malhotra, Villafuerte and Simonson.
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