Spectral optical coherence tomography findings in patients with ocular toxoplasmosis: A case series study.
EZ, Ellipsoid zone
Ocular toxoplasmosis
RPE, Retinal pigment epithelium
SD-OCT, Spectral domain optical coherence tomography
SS-OCT, Swept-source optical coherence tomography
Spectral optical coherence tomography
Uveitis
Journal
Annals of medicine and surgery (2012)
ISSN: 2049-0801
Titre abrégé: Ann Med Surg (Lond)
Pays: England
ID NLM: 101616869
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
26
01
2020
revised:
08
04
2020
accepted:
13
04
2020
entrez:
22
5
2020
pubmed:
22
5
2020
medline:
22
5
2020
Statut:
epublish
Résumé
Ocular toxoplasmosis is the most common cause of infectious uveitis worldwide. The diagnosis of ocular toxoplasmosis is primarily clinical when it is a typical presentation.With an atypical presentation in the fundus, parasitological diagnosis is a decisive contribution, as well as multimodal imaging. The aim of this study was to investigate vitreal, retinal, and choroidal morphologic changes in active and scarred toxoplasmosis lesions using swept source optical coherence tomography. To our knowledge, it is the first study in Tunisia which describes with precision the retinochoroidal lesions caused by A retrospective analysis of fifteen patients diagnosed with ocular toxoplasmosis was conducted. The patients were examined at ophthalmology service of Farhat Hached Hospital in Sousse Tunisia between January 2002 and December 2019. Complete ophthalmologic examination including best-corrected visual acuity, slit lamp biomicroscopy, dilated biomicroscopic and fundus examinations, colour fundus photography as well as fluorescein angiography and OCT were done at the initial visit and during follow-up. In the acute phase, thickening, hyper-reflectivity of the neurosensory retina, posterior shading, bumping of the RPE, hyporeflectivity and thickening of choroid were found in 86,6% of patients. During follow-up, neurosensory retinal layers thinning and disorganization, interrupting ofthe ellipsoid zone (EZ), and RPE hyper reflective were noticed in 73% of patients. The choroid became thin and more hyperreflective in 73% of patients. Multiple hyperreflective dots in the vitreous cavity and posterior hyaloid thickening were demonstrated in the acute phase in 60% of patients, with complete resolution and detachment of the posterior hyaloid in the scarred lesions. The SS-OCT is an important adjunctive imaging modality in the diagnosis and follow-up of patients with ocular toxoplasmosis.
Identifiants
pubmed: 32435471
doi: 10.1016/j.amsu.2020.04.008
pii: S2049-0801(20)30049-2
pmc: PMC7231836
doi:
Types de publication
Case Reports
Langues
eng
Pagination
125-128Informations de copyright
© 2020 The Authors.
Déclaration de conflit d'intérêts
The authors have no conflict of interest to declare.
Références
Int J Surg. 2018 Dec;60:279-282
pubmed: 30359781
Am J Ophthalmol. 2003 Dec;136(6):973-88
pubmed: 14644206
Curr Opin Ophthalmol. 2002 Dec;13(6):387-92
pubmed: 12441842
Ophthalmic Surg Lasers Imaging. 2009 May-Jun;40(3):336-41
pubmed: 19485306
Br J Ophthalmol. 2002 Jun;86(6):636-9
pubmed: 12034685
Eye (Lond). 2007 Jan;21(1):33-9
pubmed: 16215541
Int J Med Sci. 2009;6(3):137-8
pubmed: 19319235
Graefes Arch Clin Exp Ophthalmol. 2013 Aug;251(8):2037-45
pubmed: 23568271
Korean J Ophthalmol. 2012 Feb;26(1):58-60
pubmed: 22323888
Indian J Ophthalmol. 2007 May-Jun;55(3):173-83
pubmed: 17456933
Retin Cases Brief Rep. 2016 Summer;10(3):217-20
pubmed: 26510002
Ophthalmology. 2002 May;109(5):869-78
pubmed: 11986090
Acta Ophthalmol. 2013 Feb;91(1):e41-7
pubmed: 22970804