Elevated microRNA-125b inhibits cytotrophoblast invasion and impairs endothelial cell function in preeclampsia.

Epigenetics Pre-eclampsia

Journal

Cell death discovery
ISSN: 2058-7716
Titre abrégé: Cell Death Discov
Pays: United States
ID NLM: 101665035

Informations de publication

Date de publication:
2020
Historique:
received: 02 03 2020
revised: 17 04 2020
accepted: 23 04 2020
entrez: 22 5 2020
pubmed: 22 5 2020
medline: 22 5 2020
Statut: epublish

Résumé

Preeclampsia (PE) is a life-threatening disorder of human pregnancy affecting 5-8% of all pregnancies. Currently, PE remains an elusive complicated and heterogenous medical condition with no early marker or symptoms is recognized for this serious pregnancy complications. Here, we profiled the plasma miRNA expression patterns associated with preeclampsia and found 16 miRNAs were deregulated (

Identifiants

pubmed: 32435510
doi: 10.1038/s41420-020-0269-0
pii: 269
pmc: PMC7220944
doi:

Types de publication

Journal Article

Langues

eng

Pagination

35

Informations de copyright

© The Author(s) 2020.

Déclaration de conflit d'intérêts

Conflict of interestThe authors declare that they have no conflict of interest.

Références

Hypertension. 2013 Apr;61(4):767-9
pubmed: 23424230
Cancer Res. 2013 Aug 15;73(16):5253-65
pubmed: 23774215
J Cell Physiol. 2020 Apr;235(4):3235-3248
pubmed: 31595979
Hypertension. 2020 Mar;75(3):762-771
pubmed: 31983308
Nat Rev Mol Cell Biol. 2019 Jan;20(1):21-37
pubmed: 30108335
Pregnancy Hypertens. 2018 Jul;13:291-310
pubmed: 29803330
Oncogene. 2012 May 17;31(20):2535-44
pubmed: 21996748
J Cell Physiol. 2019 Jul;234(7):11149-11155
pubmed: 30443949
PLoS One. 2018 Jan 2;13(1):e0190654
pubmed: 29293682
Hypertension. 2008 Nov;52(5):873-80
pubmed: 18824660
Lancet. 2016 Mar 5;387(10022):999-1011
pubmed: 26342729
Hypertension. 2014 Oct;64(4):839-45
pubmed: 24980667
J Clin Endocrinol Metab. 2012 Jun;97(6):E1051-9
pubmed: 22438230
Biol Reprod. 2013 May 23;88(5):130
pubmed: 23575145
Sci Rep. 2014 May 08;4:4882
pubmed: 24811064
Reproduction. 2018 Jun;155(6):R259-R271
pubmed: 29615475
Biol Reprod. 2015 Jan;92(1):21
pubmed: 25472924
J Biol Chem. 2018 Dec 7;293(49):18989-19000
pubmed: 30279269
Channels (Austin). 2019 Dec;13(1):321-330
pubmed: 31354026
Am J Obstet Gynecol. 2009 Jun;200(6):661.e1-7
pubmed: 19285651
Hypertension. 2013 Apr;61(4):864-72
pubmed: 23424236
Hypertension. 2017 Apr;69(4):580-581
pubmed: 28193710
J Clin Invest. 2008 Jan;118(1):89-99
pubmed: 18064304
Biochem Biophys Res Commun. 2014 Oct 10;453(1):57-63
pubmed: 25251470
J Cell Mol Med. 2019 Sep;23(9):5884-5894
pubmed: 31301111
Inflamm Res. 2019 Aug;68(8):643-654
pubmed: 31143973
PLoS One. 2013;8(2):e56647
pubmed: 23437196
J Cell Physiol. 2019 Feb;234(2):1052-1061
pubmed: 30256424
Mol Ther. 2018 Sep 5;26(9):2189-2205
pubmed: 30061037
J Cell Biochem. 2013 Sep;114(9):2148-59
pubmed: 23553946
Biol Reprod. 2009 Oct;81(4):717-29
pubmed: 19494253
Front Endocrinol (Lausanne). 2018 Aug 03;9:402
pubmed: 30123182
Front Oncol. 2019 Jul 12;9:614
pubmed: 31355137
Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):E7069-E7076
pubmed: 27791094
Reproduction. 2017 Sep;154(3):217-228
pubmed: 28592665
PLoS One. 2016 Dec 9;11(12):e0166940
pubmed: 27935985
Am J Obstet Gynecol. 2018 Feb;218(2):249.e1-249.e12
pubmed: 29155142
Am J Physiol Endocrinol Metab. 2013 Apr 15;304(8):E836-43
pubmed: 23443922
Development. 2017 Oct 15;144(20):3731-3743
pubmed: 28935707
Circ Res. 2019 Mar 29;124(7):1094-1112
pubmed: 30920918
J Cell Sci. 2014 Mar 15;127(Pt 6):1169-78
pubmed: 24463821
Oncogene. 2013 Jan 24;32(4):414-21
pubmed: 22391569
Cell Res. 2008 Oct;18(10):997-1006
pubmed: 18766170
Histol Histopathol. 2008 Aug;23(8):965-72
pubmed: 18498071
Nat Rev Nephrol. 2019 May;15(5):275-289
pubmed: 30792480
Lancet. 2006 Apr 1;367(9516):1066-1074
pubmed: 16581405
Hypertension. 2014 Jun;63(6):1276-84
pubmed: 24664294
Cell Commun Signal. 2014 Apr 28;12:30
pubmed: 24774301
Elife. 2015 Aug 12;4:
pubmed: 26267216

Auteurs

Qinghua Li (Q)

1School of Public Health, Weifang Medical University, Weifang, 261053 Shandong China.

Yangyang Han (Y)

2School of Biosciences, Weifang Medical University, Weifang, 261053 Shandong China.
Shandong Province Key Laboratory of Biopharmaceutics, Weifang, 261053 Shandong China.

Peng Xu (P)

4School of Life Science, Shanxi University, Taiyuan, 030006 Shanxi China.

Lingxuan Yin (L)

2School of Biosciences, Weifang Medical University, Weifang, 261053 Shandong China.
Shandong Province Key Laboratory of Biopharmaceutics, Weifang, 261053 Shandong China.

Yanru Si (Y)

2School of Biosciences, Weifang Medical University, Weifang, 261053 Shandong China.
Shandong Province Key Laboratory of Biopharmaceutics, Weifang, 261053 Shandong China.

Cuijuan Zhang (C)

5Department of Obstetrics, Affiliated Hospital of Weifang Medical University, Weifang, 261031 Shandong China.

Yuhan Meng (Y)

6Center for Reproductive Medicine, Affiliated Hospital of Weifang Medical University, Weifang, 261042 Shandong China.

Weiguo Feng (W)

2School of Biosciences, Weifang Medical University, Weifang, 261053 Shandong China.
Shandong Province Key Laboratory of Biopharmaceutics, Weifang, 261053 Shandong China.

Zhifang Pan (Z)

2School of Biosciences, Weifang Medical University, Weifang, 261053 Shandong China.
Shandong Province Key Laboratory of Biopharmaceutics, Weifang, 261053 Shandong China.

Zhiqin Gao (Z)

2School of Biosciences, Weifang Medical University, Weifang, 261053 Shandong China.
Shandong Province Key Laboratory of Biopharmaceutics, Weifang, 261053 Shandong China.

Jie Li (J)

5Department of Obstetrics, Affiliated Hospital of Weifang Medical University, Weifang, 261031 Shandong China.

Weiwei Yang (W)

2School of Biosciences, Weifang Medical University, Weifang, 261053 Shandong China.
Shandong Province Key Laboratory of Biopharmaceutics, Weifang, 261053 Shandong China.

Classifications MeSH