Evaluation of an organ-based tube current modulation tool in pediatric CT examinations.

To investigate the effect of an organ-based tube current modulation (OTCM) technique on organ absorbed dose and assess image quality in pediatric CT examinations. Four physical anthropomorphic phantoms that represent the average individual as neonate, 1-year-old, 5-year-old, and 10-year-old were used. Standard head and thorax acquisitions were performed with automatic tube current modulation (ATCM) and ATCM+OTCM. Dose calculations were performed by means of Monte Carlo simulations. Radiation dose was measured for superficial and centrally located radiosensitive organs. The angular range of the OTCM exposure window was determined for different tube rotation times (t) by means of a solid-state detector. Image noise was measured as the standard deviation of the Hounsfield unit value in regions of interest drawn at selected anatomical sites. ATCM+OTCM resulted in a reduction of radiation dose to all radiosensitive organs. In head, eye lens dose was reduced by up to 13% in ATCM+OTCM compared with ATCM. In thorax, the corresponding reduction for breast dose was up to 10%. The angular range of the OTCM exposure window decreased with t. For t = 0.4 s, the angular range was limited to 74° in head and 135° for thorax. Image noise was significantly increased in ATCM+OTCM acquisitions across most examined phantoms (p < 0.05). OTCM reduces radiation dose to exposed radiosensitive organs with the eye lens and breast buds exhibiting the highest dose reduction. The OTCM exposure window is narrowed at short t. An increase in noise is inevitable in images located within the OTCM-activated imaged volume. • In pediatric CT, organ-based tube current modulation reduces radiation dose to all major primarily exposed radiosensitive organs. • Image noise increases within the organ-based tube current modulation enabled imaged volume. • The angular range of the organ-based tube current modulation low exposure window is reduced with tube rotation time.