Pollen Proteases Play Multiple Roles in Allergic Disorders.
IL-6
IL-8 and PAR-2
allergy
pollen proteases
transepithelial permeability
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
19 May 2020
19 May 2020
Historique:
received:
25
04
2020
revised:
14
05
2020
accepted:
16
05
2020
entrez:
23
5
2020
pubmed:
23
5
2020
medline:
11
2
2021
Statut:
epublish
Résumé
Allergic diseases are a major health concern worldwide. Pollens are important triggers for allergic rhinitis, conjunctivitis and asthma. Proteases released upon pollen grain hydration appear to play a major role in the typical immunological and inflammatory responses that occur in patients with allergic disorders. In this study, we aimed to identify specific proteolytic activity in a set of pollens with diverse allergenic potential. Diffusates from
Identifiants
pubmed: 32438574
pii: ijms21103578
doi: 10.3390/ijms21103578
pmc: PMC7278992
pii:
doi:
Substances chimiques
Interleukin-6
0
Interleukin-8
0
Receptor, PAR-2
0
Water
059QF0KO0R
Peptide Hydrolases
EC 3.4.-
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Fundação para a Ciência e a Tecnologia
ID : PTDC/SAU-ESA/72571/2006
Organisme : Fundação para a Ciência e a Tecnologia
ID : PEst-C/SAU/LA0001/2013-2014
Organisme : Fundação para a Ciência e a Tecnologia
ID : UIDB/04539/2020
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