Is breast conserving therapy better than mastectomy? Surgeons must speak out.
Breast conserving therapy
Mastectomy
Radiotherapy
Journal
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
ISSN: 1532-2157
Titre abrégé: Eur J Surg Oncol
Pays: England
ID NLM: 8504356
Informations de publication
Date de publication:
08 2020
08 2020
Historique:
received:
06
04
2020
revised:
01
05
2020
accepted:
08
05
2020
pubmed:
23
5
2020
medline:
1
1
2021
entrez:
23
5
2020
Statut:
ppublish
Résumé
Several population-based studies suggest that breast conserving surgery followed by radiotherapy (BCT) may provide longer overall survival than mastectomy. Better locoregional control after BCT due to improvements of preoperative imaging, oncoplastic surgery and radiotherapy, as well as the recent trend towards surgical de-escalation may be involved. Alternatively, modern radiotherapy may have such an improved benefit/risk ratio that its survival advantage now stands out more clearly. However, since the therapeutic equivalence of BCT and mastectomy was demonstrated by several randomised trials, this information cannot be disregarded, nor radiotherapy should be used to compensate for inadequate surgery. Both BCT and mastectomy are likely here to stay as clinical presentation of breast cancer is highly variable, and women desires may transcend a rational balance of pros and cons between the two surgical approaches. Our duty as surgeons is to lead the multidisciplinary board and accompany the patients along this difficult decision-making process.
Identifiants
pubmed: 32439264
pii: S0748-7983(20)30458-3
doi: 10.1016/j.ejso.2020.05.005
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1551-1553Informations de copyright
Copyright © 2020 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest None.