Palladium-Catalyzed Amination/Dearomatization Reaction of Indoles and Benzofurans.
Journal
The Journal of organic chemistry
ISSN: 1520-6904
Titre abrégé: J Org Chem
Pays: United States
ID NLM: 2985193R
Informations de publication
Date de publication:
19 06 2020
19 06 2020
Historique:
pubmed:
23
5
2020
medline:
23
5
2020
entrez:
23
5
2020
Statut:
ppublish
Résumé
This report describes a palladium-catalyzed dearomatization and amination tandem reaction of 2,3-disubstituted indoles and benzofurans via the Catellani strategy. This reaction provides a new method for the construction of amino-substituted indoline-fused cyclic and benzofuran spiro compounds in good yields. The reaction has broad functional group compatibility and substrate scope.
Identifiants
pubmed: 32441518
doi: 10.1021/acs.joc.0c00475
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM