ATP1A3: an unusual antigen to consider in patients with subacute ataxia and vertical gaze palsy.
Anti-ATP1A3 encephalitis
Cerebellar ataxia
Paraneoplastic syndrome
Vertical ophthalmoparesis
Journal
Multiple sclerosis and related disorders
ISSN: 2211-0356
Titre abrégé: Mult Scler Relat Disord
Pays: Netherlands
ID NLM: 101580247
Informations de publication
Date de publication:
Aug 2020
Aug 2020
Historique:
received:
28
08
2019
revised:
06
01
2020
accepted:
26
04
2020
pubmed:
23
5
2020
medline:
11
5
2021
entrez:
23
5
2020
Statut:
ppublish
Résumé
The anti-ATP1A3 antibody seems to be directed against a neuronal and cardiac surface protein of the proton ATPase. It was recently identified in a patient with a paraneoplastic syndrome characterized by cerebellar, neuro-ophthalmologic and other neurological symptoms. We report another patient with a similar clinical and radiological syndrome but with a different associated tumor and outcome.
Identifiants
pubmed: 32442884
pii: S2211-0348(20)30236-4
doi: 10.1016/j.msard.2020.102160
pii:
doi:
Substances chimiques
ATP1A3 protein, human
0
Sodium-Potassium-Exchanging ATPase
EC 7.2.2.13
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
102160Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no conflicts of interest regarding the publication of this paper.