Selenium intake and status of postpartum women and postnatal depression during the first year after childbirth in New Zealand - Mother and Infant Nutrition Investigation (MINI) study.

Breastfeeding EPDS Infants Postnatal depression Postpartum Selenium

Journal

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
ISSN: 1878-3252
Titre abrégé: J Trace Elem Med Biol
Pays: Germany
ID NLM: 9508274

Informations de publication

Date de publication:
08 May 2020
Historique:
received: 22 01 2020
revised: 02 03 2020
accepted: 23 03 2020
pubmed: 23 5 2020
medline: 23 5 2020
entrez: 23 5 2020
Statut: aheadofprint

Résumé

Selenium (Se) plays an important role in selenoproteins as an antioxidant, and is involved in thyroid function, mental health and child development. Selenium is low in the local food supplies in NZ. Low selenium intake has been reported in women of childbearing age and postmenopausal women, however, there is little research relating to breastfeeding women and their infants. The study investigates maternal and infant selenium intake and status during the first year postpartum, and possible relationships to postnatal depression and anxiety. The Mother and Infant Nutrition Investigation (MINI) study is an observational longitudinal cohort study. In total 87 breastfeeding mother-infant pairs were recruited and followed up at 3, 6 and 12 months postpartum. Maternal selenium intake was estimated from a four-day diet diary (4DDD). Selenium concentrations were measured in maternal spot urine, breastmilk and plasma; and infant spot urine samples. Postnatal depression was screened by the Edinburgh Postnatal Depression Scale (EPDS) questionnaire. Median maternal selenium intake was 62 (50, 84) μg/day, with 56 % below the Estimated Average Requirement (EAR) of 65 μg/day. At 3, 6, and 12 months postpartum, median maternal urinary selenium:creatinine ratios were 29.0 (22.4, 42.0), 29.5 (23.1, 28.4), and 30.9 (24.3, 35.3) μg/g; median infant urinary selenium concentrations (IUSC) were 8 (6,13), 11 (6, 15), and 24 (10, 40) μg/L; median breastmilk selenium concentrations (BMSC) were 13 (11, 14), 11 (9, 11) and 12 (11, 13) μg/L; 18 %, 11 % and 14 % of women reported probable minor depression based on the EPDS scores equal or above 10. Estimated median infant selenium intake at 3 and 6 months were 9 (8, 11) and 8 (7, 10) μg/day with 85 % and 93 % below the Adequate Intake of 12 μg/day. Median maternal plasma selenium was 105.8 μg/L at 6 months postpartum. Minor depression at three months postpartum was significantly different across tertiles of plasma selenium concentrations (p = 0.041). Suboptimal selenium intake was observed among breastfeeding mothers and their infants in the MINI study. Potentially, some women had insufficient selenium status. Relation between selenium status and risk of postnatal depression and anxiety was inconclusive.Further research is required to explore effects on maternal thyroid function and infant neurodevelopment among women with inadequate selenium intake and status.

Sections du résumé

BACKGROUND BACKGROUND
Selenium (Se) plays an important role in selenoproteins as an antioxidant, and is involved in thyroid function, mental health and child development. Selenium is low in the local food supplies in NZ. Low selenium intake has been reported in women of childbearing age and postmenopausal women, however, there is little research relating to breastfeeding women and their infants.
PURPOSE OBJECTIVE
The study investigates maternal and infant selenium intake and status during the first year postpartum, and possible relationships to postnatal depression and anxiety.
BASIC PROCEDURES METHODS
The Mother and Infant Nutrition Investigation (MINI) study is an observational longitudinal cohort study. In total 87 breastfeeding mother-infant pairs were recruited and followed up at 3, 6 and 12 months postpartum. Maternal selenium intake was estimated from a four-day diet diary (4DDD). Selenium concentrations were measured in maternal spot urine, breastmilk and plasma; and infant spot urine samples. Postnatal depression was screened by the Edinburgh Postnatal Depression Scale (EPDS) questionnaire.
MAIN FINDINGS RESULTS
Median maternal selenium intake was 62 (50, 84) μg/day, with 56 % below the Estimated Average Requirement (EAR) of 65 μg/day. At 3, 6, and 12 months postpartum, median maternal urinary selenium:creatinine ratios were 29.0 (22.4, 42.0), 29.5 (23.1, 28.4), and 30.9 (24.3, 35.3) μg/g; median infant urinary selenium concentrations (IUSC) were 8 (6,13), 11 (6, 15), and 24 (10, 40) μg/L; median breastmilk selenium concentrations (BMSC) were 13 (11, 14), 11 (9, 11) and 12 (11, 13) μg/L; 18 %, 11 % and 14 % of women reported probable minor depression based on the EPDS scores equal or above 10. Estimated median infant selenium intake at 3 and 6 months were 9 (8, 11) and 8 (7, 10) μg/day with 85 % and 93 % below the Adequate Intake of 12 μg/day. Median maternal plasma selenium was 105.8 μg/L at 6 months postpartum. Minor depression at three months postpartum was significantly different across tertiles of plasma selenium concentrations (p = 0.041).
PRINCIPLE CONCLUSIONS CONCLUSIONS
Suboptimal selenium intake was observed among breastfeeding mothers and their infants in the MINI study. Potentially, some women had insufficient selenium status. Relation between selenium status and risk of postnatal depression and anxiety was inconclusive.Further research is required to explore effects on maternal thyroid function and infant neurodevelopment among women with inadequate selenium intake and status.

Identifiants

DOI: 10.1016/j.jtemb.2020.126503 PMID: 32442890
pubmed: 32442890
pii: S0946-672X(20)30068-7
doi: 10.1016/j.jtemb.2020.126503
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

126503

Informations de copyright

Copyright © 2020 Elsevier GmbH. All rights reserved.

Auteurs

Ying Jin (Y)

R J Hill Laboratories Limited, Hamilton, New Zealand; Canterbury Health Laboratories, Christchurch, New Zealand; Nutrition Laboratory, Massey University, Palmerston North, New Zealand; School of Health Sciences, College of Health, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. Electronic address: Y.JIN@MASSEY.AC.NZ.

Jane Coad (J)

R J Hill Laboratories Limited, Hamilton, New Zealand; Canterbury Health Laboratories, Christchurch, New Zealand; Nutrition Laboratory, Massey University, Palmerston North, New Zealand; Nutrition Science, School of Food and Advanced Technology, College of Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. Electronic address: J.COAD@MASSEY.AC.NZ.

Rachael Pond (R)

R J Hill Laboratories Limited, Hamilton, New Zealand; Canterbury Health Laboratories, Christchurch, New Zealand; Nutrition Laboratory, Massey University, Palmerston North, New Zealand; Institute of Education, College of Humanities and Social Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. Electronic address: R.L.POND@MASSEY.AC.NZ.

Nick Kim (N)

R J Hill Laboratories Limited, Hamilton, New Zealand; Canterbury Health Laboratories, Christchurch, New Zealand; Nutrition Laboratory, Massey University, Palmerston North, New Zealand; School of Health Sciences, College of Health, Massey University, Mt Cook, Wellington 6021, New Zealand. Electronic address: N.KIM@MASSEY.AC.NZ.

Louise Brough (L)

R J Hill Laboratories Limited, Hamilton, New Zealand; Canterbury Health Laboratories, Christchurch, New Zealand; Nutrition Laboratory, Massey University, Palmerston North, New Zealand; Nutrition Science, School of Food and Advanced Technology, College of Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. Electronic address: L.BROUGH@MASSEY.AC.NZ.

Classifications MeSH