Biochemical predictors of preterm birth in twin pregnancies: A systematic review involving 6077 twin pregnancies.


Journal

European journal of obstetrics, gynecology, and reproductive biology
ISSN: 1872-7654
Titre abrégé: Eur J Obstet Gynecol Reprod Biol
Pays: Ireland
ID NLM: 0375672

Informations de publication

Date de publication:
Jul 2020
Historique:
received: 31 01 2020
accepted: 02 04 2020
pubmed: 24 5 2020
medline: 15 5 2021
entrez: 24 5 2020
Statut: ppublish

Résumé

In women with twin pregnancies biomarkers are not used to predict preterm birth in clinical practice. This systematic review assessed the risk of both spontaneous and iatrogenic preterm birth in twin pregnancies based on biochemical predictors. We searched the electronic databases from January 1990 to June 2019 without language restrictions. All studies on twin pregnancies where biochemical predictors and preterm birth were evaluated were included. We reported our findings as odds ratio (OR) with 95 % confidence intervals (CI) and pooled the estimates using random-effects meta-analysis for various predictor thresholds. From 12,623 citations, we included 33 studies involving 6077 pregnancies. The odds of preterm birth <28 weeks (OR 12.06, 95 % CI 4.90-29.70, I

Identifiants

pubmed: 32446146
pii: S0301-2115(20)30183-4
doi: 10.1016/j.ejogrb.2020.04.015
pii:
doi:

Substances chimiques

Fibronectins 0

Types de publication

Journal Article Meta-Analysis Review Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

130-142

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Auteurs

Shemoon Marleen (S)

Barts Research Centre for Women's Health (BARC), Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK; World Health Organization (WHO) Collaborating Centre for Women's Health, Queen Mary University of London, London, UK. Electronic address: fathimamarleen@qmul.ac.uk.

Chamalika Dias (C)

University of Colombo, Sri Lanka.

Rebecca MacGregor (R)

Royal London Hospital, Barts Health NHS Trust, London, UK.

John Allotey (J)

Barts Research Centre for Women's Health (BARC), Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK; World Health Organization (WHO) Collaborating Centre for Women's Health, Queen Mary University of London, London, UK; Multidisciplinary Evidence Synthesis Hub (mEsh), Queen Mary University of London, London, UK.

Joseph Aquilina (J)

Royal London Hospital, Barts Health NHS Trust, London, UK.

Asma Khalil (A)

St George's University Hospitals NHS Foundation Trust, London, UK; Molecular and Clinical Sciences Research Institute, St George's Medical School, University of London, UK.

Shakila Thangaratinam (S)

Barts Research Centre for Women's Health (BARC), Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK; World Health Organization (WHO) Collaborating Centre for Women's Health, Queen Mary University of London, London, UK; Multidisciplinary Evidence Synthesis Hub (mEsh), Queen Mary University of London, London, UK.

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Classifications MeSH