Mechanism, frequency, transfusion and outcome of severe trauma in coagulopathic paediatric patients.
Coagulopathy
Haemorrhage
Mortality
Paediatric trauma
Transfusion
Journal
European journal of trauma and emergency surgery : official publication of the European Trauma Society
ISSN: 1863-9941
Titre abrégé: Eur J Trauma Emerg Surg
Pays: Germany
ID NLM: 101313350
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
received:
08
11
2019
accepted:
16
05
2020
pubmed:
26
5
2020
medline:
11
2
2022
entrez:
26
5
2020
Statut:
ppublish
Résumé
Acute traumatic coagulopathy can result in uncontrolled haemorrhage responsible for the majority of early deaths after adult trauma. Data on the frequency, transfusion practice and outcome of severe trauma haemorrhage in paediatric patients are inconsistent. Datasets from paediatric trauma patients were retrieved from the registry of the German trauma society (TR-DGU 5351 primary admitted children ≤ 17 years with an abbreviated injury scale (AIS) ≥ 3 and complete datasets were included. The prevalence of coagulopathy was 13.7% (733/5351). The majority of the children sustained blunt trauma (more than 90% independent of age group) and a combination of traumatic brain injury (TBI) and any other trauma in more than 60% (A, C, D) and in 53.8% in group B. Coagulopathy occurred the most among the youngest (A: 18.2%), followed by all other age groups with approximately 13%. Overall mortality was the highest in the youngest (A: 40.9%) and among the youngest patients with traumatic brain injury (A: 71.4% and B: 47.1%). Transfusion of packed red blood cells (pRBCs) and fresh frozen plasma (FFPs) occurred almost in a 2:1 ratio (or less) across all age subgroups. Traumatic haemorrhage in association with coagulopathy and severe shock is a major challenge in paediatric trauma across all age groups.
Identifiants
pubmed: 32448940
doi: 10.1007/s00068-020-01398-x
pii: 10.1007/s00068-020-01398-x
pmc: PMC7245642
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
153-161Informations de copyright
© 2020. The Author(s).
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