Extra-respiratory manifestations of COVID-19.
COVID-19
Epidemiology
Extra-respiratory manifestations
SARS-CoV-2
Journal
International journal of antimicrobial agents
ISSN: 1872-7913
Titre abrégé: Int J Antimicrob Agents
Pays: Netherlands
ID NLM: 9111860
Informations de publication
Date de publication:
Aug 2020
Aug 2020
Historique:
received:
23
04
2020
revised:
14
05
2020
accepted:
14
05
2020
pubmed:
26
5
2020
medline:
22
8
2020
entrez:
26
5
2020
Statut:
ppublish
Résumé
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global health threat. Although most patients with COVID-19 manifest fever and respiratory tract symptoms, SARS-CoV-2 infection may also involve other organs/systems and present with extra-respiratory manifestations, including cardiac, gastrointestinal, hepatic, renal, neurological, olfactory, gustatory, ocular, cutaneous and haematological symptoms. Occasionally, these extra-respiratory symptoms/signs represent the initial presentation of SARS-CoV-2 infection, prior to fever or respiratory manifestations. Therefore, this comprehensive review of the extra-respiratory manifestations of COVID-19 is intended to help clinicians better understand the range of clinical presentations associated with SARS-CoV-2 infection, allowing the consideration of COVID-19 in differential diagnoses. A screening test for SARS-CoV-2 should be performed when patients have these extra-respiratory manifestations. In addition, clinicians should be alerted to the adverse effects of anti-SARS-CoV-2 agents that can mimic the extra-respiratory manifestations of COVID-19. Moreover, some extra-respiratory manifestations, such as ocular and gastrointestinal involvement, may be caused by direct invasion of SARS-CoV-2. Therefore, protective measures should be taken while managing the associated clinical specimens. Finally, several extra-respiratory manifestations, such as cardiac involvement, acute kidney injury, coagulation disorders and thrombotic complications, could be associated with a poor prognosis.
Identifiants
pubmed: 32450197
pii: S0924-8579(20)30187-4
doi: 10.1016/j.ijantimicag.2020.106024
pmc: PMC7243791
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
106024Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.
Références
J Clin Virol. 2020 Jun;127:104366
pubmed: 32302954
J Cardiovasc Electrophysiol. 2020 May;31(5):1003-1008
pubmed: 32270559
Lancet. 2020 Mar 28;395(10229):1054-1062
pubmed: 32171076
Invest Ophthalmol Vis Sci. 2007 Jul;48(7):3301-11
pubmed: 17591902
Rev Chilena Infectol. 2018;35(5):518-530
pubmed: 30724999
Nat Microbiol. 2020 Apr;5(4):562-569
pubmed: 32094589
Arthritis Rheum. 2008 Oct;58(10):2968-80
pubmed: 18821691
Eur Heart J. 2021 Jan 7;42(2):206
pubmed: 32176300
Thromb Res. 2020 Jul;191:145-147
pubmed: 32291094
JAMA Neurol. 2020 Jun 1;77(6):683-690
pubmed: 32275288
JAMA Cardiol. 2020 Jul 1;5(7):819-824
pubmed: 32219357
Lancet Gastroenterol Hepatol. 2020 May;5(5):428-430
pubmed: 32145190
Br J Ophthalmol. 2020 Mar;104(3):297-298
pubmed: 32086236
Clin Infect Dis. 2020 Jul 28;71(15):889-890
pubmed: 32215618
Emerg Infect Dis. 2020 Jun;26(6):1337-1339
pubmed: 32150527
J Eur Acad Dermatol Venereol. 2020 May;34(5):e212-e213
pubmed: 32215952
Pharmacol Ther. 2020 May;209:107512
pubmed: 32097670
JAMA. 2020 Mar 17;323(11):1061-1069
pubmed: 32031570
JAMA Cardiol. 2020 Jul 1;5(7):811-818
pubmed: 32219356
N Engl J Med. 2020 Apr 30;382(18):1708-1720
pubmed: 32109013
Int J Antimicrob Agents. 2020 Apr;55(4):105946
pubmed: 32199877
Eur Arch Otorhinolaryngol. 2020 Aug;277(8):2251-2261
pubmed: 32253535
Int J Antimicrob Agents. 2020 Mar;55(3):105924
pubmed: 32081636
J Med Virol. 2020 Jun;92(6):680-682
pubmed: 32124995
Dermatol Online J. 2019 Jan 15;25(1):
pubmed: 30710895
Zhonghua Xue Ye Xue Za Zhi. 2020 Mar 28;41(0):E006
pubmed: 32220276
BMJ. 2020 Feb 19;368:m606
pubmed: 32075786
J Microbiol Immunol Infect. 2020 Jun;53(3):413-418
pubmed: 32224117
Dermatol Clin. 2019 Jan;37(1):95-105
pubmed: 30466692
ACS Chem Neurosci. 2020 Apr 1;11(7):995-998
pubmed: 32167747
Lancet Infect Dis. 2020 Apr;20(4):425-434
pubmed: 32105637
J Infect. 2020 Jun;80(6):656-665
pubmed: 32283155
J Pathol. 2015 Jan;235(2):277-87
pubmed: 25294743
Br J Ophthalmol. 2020 Jun;104(6):748-751
pubmed: 32265202
Br J Ophthalmol. 1996 Feb;80(2):159-63
pubmed: 8814748
Gastroenterology. 2020 Jul;159(1):81-95
pubmed: 32251668
Gut. 2020 Jun;69(6):997-1001
pubmed: 32241899
J Am Acad Dermatol. 2020 Aug;83(2):700
pubmed: 32283229
Am J Trop Med Hyg. 2018 Feb;98(2):382-388
pubmed: 29210346
J Pathol. 2004 Jun;203(2):631-7
pubmed: 15141377
Cutis. 2018 Nov;102(5):353-356
pubmed: 30566537
JAMA Cardiol. 2020 Jul 1;5(7):802-810
pubmed: 32211816
Diabetes Metab Syndr. 2020 May - Jun;14(3):247-250
pubmed: 32247212
J Microbiol Immunol Infect. 2020 Jun;53(3):436-443
pubmed: 32307245
Clin Chem Lab Med. 2020 Jun 25;58(7):1021-1028
pubmed: 32286245
Nat Rev Nephrol. 2020 Jun;16(6):308-310
pubmed: 32273593
Gastroenterology. 2020 May;158(6):1518-1519
pubmed: 32142785
Int J Infect Dis. 2020 May;94:55-58
pubmed: 32251791
N Engl J Med. 2020 Jun 25;382(26):2574-2576
pubmed: 32302082
Thromb Res. 2020 Jun;190:58-59
pubmed: 32302782
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Brain Behav Immun. 2020 Jul;87:18-22
pubmed: 32240762
J Med Virol. 2020 Oct;92(10):1902-1914
pubmed: 32293716
JAMA Ophthalmol. 2020 May 01;138(5):575-578
pubmed: 32232433
J Thromb Haemost. 2020 May;18(5):1094-1099
pubmed: 32220112
J Thromb Haemost. 2020 Jul;18(7):1738-1742
pubmed: 32302438
J Microbiol Immunol Infect. 2020 Jun;53(3):404-412
pubmed: 32173241
N Engl J Med. 2020 Apr 23;382(17):e38
pubmed: 32268022
Lancet. 2020 Feb 15;395(10223):507-513
pubmed: 32007143
Brain Behav Immun. 2020 Aug;88:945-946
pubmed: 32283294
J Clin Microbiol. 2020 May 26;58(6):
pubmed: 32245835
N Engl J Med. 2020 Jun 11;382(24):2327-2336
pubmed: 32275812
Int J Oral Sci. 2020 Feb 24;12(1):8
pubmed: 32094336
Lancet Respir Med. 2020 May;8(5):475-481
pubmed: 32105632
Chin Med J (Engl). 2020 May 5;133(9):1039-1043
pubmed: 32118639