Rosette Trajectories Enable Ungated, Motion-Robust, Simultaneous Cardiac and Liver T
Adult
Artifacts
Female
Ferrosoferric Oxide
/ analysis
Healthy Volunteers
Heart
/ anatomy & histology
Humans
Image Processing, Computer-Assisted
/ methods
Liver
/ anatomy & histology
Magnetic Resonance Imaging
/ methods
Male
Motion
Phantoms, Imaging
Prospective Studies
Reference Values
Reproducibility of Results
Iron
T2*
non-Cartesian
rosette
Journal
Journal of magnetic resonance imaging : JMRI
ISSN: 1522-2586
Titre abrégé: J Magn Reson Imaging
Pays: United States
ID NLM: 9105850
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
received:
11
02
2020
revised:
30
04
2020
accepted:
01
05
2020
pubmed:
27
5
2020
medline:
15
12
2020
entrez:
27
5
2020
Statut:
ppublish
Résumé
Quantitative T To develop and evaluate a motion-robust, simultaneous cardiac and liver T Prospective. Six ferumoxytol-containing phantoms (26-288 μg/mL). Eight healthy subjects and 18 patients referred for clinically indicated iron overload assessment. 1.5T, 2D Cartesian and rosette gradient echo (GRE) ASSESSMENT: GRE T Linear regression, analysis of variance (ANOVA), and paired Student's t-testing were used to compare reproducibility and variability metrics in Cartesian and rosette scans. The Wilcoxon rank test was used to assess reader score comparisons and reader reliability was measured using intraclass correlation analysis. Rosette R2* (1/T Rosette k-sampling with a model-based reconstruction offers a clinically useful motion-robust T
Sections du résumé
BACKGROUND
Quantitative T
PURPOSE
To develop and evaluate a motion-robust, simultaneous cardiac and liver T
STUDY TYPE
Prospective.
PHANTOM/POPULATION
Six ferumoxytol-containing phantoms (26-288 μg/mL). Eight healthy subjects and 18 patients referred for clinically indicated iron overload assessment.
FIELD STRENGTH/SEQUENCE
1.5T, 2D Cartesian and rosette gradient echo (GRE) ASSESSMENT: GRE T
STATISTICAL TESTS
Linear regression, analysis of variance (ANOVA), and paired Student's t-testing were used to compare reproducibility and variability metrics in Cartesian and rosette scans. The Wilcoxon rank test was used to assess reader score comparisons and reader reliability was measured using intraclass correlation analysis.
RESULTS
Rosette R2* (1/T
DATA CONCLUSION
Rosette k-sampling with a model-based reconstruction offers a clinically useful motion-robust T
Identifiants
pubmed: 32452088
doi: 10.1002/jmri.27196
pmc: PMC7699670
mid: NIHMS1637768
doi:
Substances chimiques
Ferrosoferric Oxide
XM0M87F357
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1688-1698Subventions
Organisme : NIH HHS
ID : NIH R01EB026136
Pays : United States
Organisme : NIBIB NIH HHS
ID : R01 EB026136
Pays : United States
Organisme : NIH HHS
ID : NIH R01EB009690
Pays : United States
Organisme : NHLBI NIH HHS
ID : 5T32EB009035
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK117354
Pays : United States
Organisme : GE Healthcare
Pays : International
Organisme : NIH HHS
ID : R01DK117354
Pays : United States
Organisme : NIBIB NIH HHS
ID : T32 EB009653
Pays : United States
Organisme : NIBIB NIH HHS
ID : T32 EB009035
Pays : United States
Organisme : NIBIB NIH HHS
ID : R01 EB009690
Pays : United States
Informations de copyright
© 2020 International Society for Magnetic Resonance in Medicine.
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