Immunostaining With Immunoglobulin G Subclass Antibody Cocktail for Diagnosis of Type 1 Autoimmune Pancreatitis.
IgG
IgG2
IgG3
IgG4-related disease
and IgG4
antibody cocktail containing mixed IgG1
type 1 autoimmune pancreatitis
Journal
International journal of surgical pathology
ISSN: 1940-2465
Titre abrégé: Int J Surg Pathol
Pays: United States
ID NLM: 9314927
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
pubmed:
28
5
2020
medline:
22
6
2021
entrez:
28
5
2020
Statut:
ppublish
Résumé
Immunoglobulin (Ig) G4-related diseases (RDs) are systemic diseases in which serum IgG4 levels are frequently elevated. They can cause diffuse or focal tumor formation, organ swelling, and tissue thickening in organs infiltrated by IgG4 We compared AC-IgG reactivity with IgG expression in type 1 autoimmune pancreatitis (AIP), a representative IgG4-RD. We compared immunohistochemistry results using AC-IgG and IgG-only in 10 cases of AIP. The coefficient of variation (Cv) was used to analyze differences between AC-IgG and IgG findings in AIP by 13 board-certified pathologists. Although mean values for IgG AC-IgG could replace IgG to count IgG
Sections du résumé
BACKGROUND.
UNASSIGNED
Immunoglobulin (Ig) G4-related diseases (RDs) are systemic diseases in which serum IgG4 levels are frequently elevated. They can cause diffuse or focal tumor formation, organ swelling, and tissue thickening in organs infiltrated by IgG4
METHODS.
UNASSIGNED
We compared AC-IgG reactivity with IgG expression in type 1 autoimmune pancreatitis (AIP), a representative IgG4-RD. We compared immunohistochemistry results using AC-IgG and IgG-only in 10 cases of AIP. The coefficient of variation (Cv) was used to analyze differences between AC-IgG and IgG findings in AIP by 13 board-certified pathologists.
RESULTS.
UNASSIGNED
Although mean values for IgG
CONCLUSION.
UNASSIGNED
AC-IgG could replace IgG to count IgG
Identifiants
pubmed: 32456567
doi: 10.1177/1066896920924781
doi:
Substances chimiques
Immunoglobulin G
0
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM