A rare case of Actinomyces skin and soft tissue infection in an end-stage kidney disease patient with a review of the literature.


Journal

Hemodialysis international. International Symposium on Home Hemodialysis
ISSN: 1542-4758
Titre abrégé: Hemodial Int
Pays: Canada
ID NLM: 101093910

Informations de publication

Date de publication:
07 2020
Historique:
received: 01 04 2020
revised: 24 04 2020
accepted: 29 04 2020
pubmed: 28 5 2020
medline: 19 3 2021
entrez: 28 5 2020
Statut: ppublish

Résumé

End-stage kidney disease (ESKD) patients are a commonly overlooked immunocompromised population that places them at risk for rare infections. We describe the case of a 78-year-old man with a history of ESKD managed with thrice weekly in-center hemodialysis who had a prolonged episode of left elbow pain and drainage and was eventually found to have a skin and soft tissue infection from Actinomyces radingae. We review the bacteriology of Actinomyces spp. and the experiences of other providers who have treated actinomycosis in individuals with ESKD. The anatomic sites and demographics of these individuals are heterogeneous, but they all generally require a long antibiotic course with a beta-lactam and portend to a good prognosis. High index of suspicion is needed to identify rare and atypical infections in the ESKD population.

Identifiants

pubmed: 32458569
doi: 10.1111/hdi.12843
doi:

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

E40-E45

Informations de copyright

© 2020 International Society for Hemodialysis.

Références

Eleftheriadis T, Liakopoulos V, Leivaditis K, Antoniadi G, Stefanidis I. Infections in hemodialysis: A concise review-part 1: Bacteremia and respiratory infections. Hippokratia. 2011;15:12-17.
Berman SJ, Johnson EW, Nakatsu C, Alkan M, Chen R, LeDuc J. Burden of infection in patients with end-stage renal disease requiring long-term dialysis. Clin Infect Dis. 2004;39:1747-1753.
Kononen E, Wade WG. Actinomyces and related organisms in human infections. Clin Microbiol Rev. 2015;28:419-442.
Wong VK, Turmezei TD, Weston VC. Actinomycosis. BMJ. 2011;343:d6099.
Gelada K, Halli R, Mograwala H, Sethi S. Actinomycosis which impersonates malignancy. Ann Maxillofac Surg. 2018;8:358-360.
Katsenos S, Galinos I, Styliara P, Galanopoulou N, Psathakis K. Primary bronchopulmonary actinomycosis masquerading as lung cancer: Apropos of two cases and literature review. Case Rep Infect Dis. 2015;2015:609637.
Monteiro EVE, Gaspar J, Paiva C, et al. Abdominal actinomycosis misdiagnosed as liposarcoma. Autops Case Rep. 2020;10:e2020137.
Sullivan DC, Chapman SW. Bacteria that masquerade as fungi: actinomycosis/nocardia. Proc Am Thorac Soc. 2010;7:216-221.
Clarridge JE 3rd, Zhang Q. Genotypic diversity of clinical actinomyces species: Phenotype, source, and disease correlation among genospecies. J Clin Microbiol. 2002;40:3442-3448.
Sabbe LJ, Van De Merwe D, Schouls L, Bergmans A, Vaneechoutte M, Vandamme P. Clinical spectrum of infections due to the newly described Actinomyces species A. turicensis, A. radingae, and A. europaeus. J Clin Microbiol. 1999;37:8-13.
Attar KH, Waghorn D, Lyons M, Cunnick G. Rare species of actinomyces as causative pathogens in breast abscess. Breast J. 2007;13:501-505.
Barberis C, Budia M, Palombarani S, et al. Antimicrobial susceptibility of clinical isolates of Actinomyces and related genera reveals an unusual clindamycin resistance among Actinomyces urogenitalis strains. J Glob Antimicrob Resist. 2017;8:115-120.
Takeda H, Mitsuhashi Y, Kondo S. Cutaneous disseminated actinomycosis in a patient with acute lymphocytic leukemia. J Dermatol. 1998;25:37-40.
Gomes J, Pereira T, Carvalho A, Brito C. Primary cutaneous actinomycosis caused by Actinomyces meyeri as first manifestation of HIV infection. Dermatol Online J. 2011;17:5.
Cohen G, Haag-Weber M, Horl WH. Immune dysfunction in uremia. Kidney Int Suppl. 1997;62:S79-S82.
Vanholder R, Ringoir S. Infectious morbidity and defects of phagocytic function in end-stage renal disease: a review. J Am Soc Nephrol. 1993;3:1541-1554.
Lisowska KA, Pindel M, Pietruczuk K, et al. The influence of a single hemodialysis procedure on human T lymphocytes. Sci Rep. 2019;9:5041.
Fuchshuber A, Kuhnemund O, Keuth B, Lutticken R, Michalk D, Querfeld U. Pneumococcal vaccine in children and young adults with chronic renal disease. Nephrol Dial Transplant. 1996;11:468-473.
Guerin A, Buisson Y, Nutini MT, Saliou P, London G, Marchais S. Response to vaccination against tetanus in chronic haemodialysed patients. Nephrol Dial Transplant. 1992;7:323-326.
Kara IH, Yilmaz ME, Suner A, Kadiroglu AK, Isikoglu B. The evaluation of immune responses that occur after HBV infection and HBV vaccination in hemodialysis patients. Vaccine. 2004;22:3963-3967.
De Santo NG, Altucci P, Giordano C. Actinomyces peritonitis associated with dialysis. Nephron. 1976;16:236-239.
Benevent DDF, Ozanne P, Lagarde C, Mounier M. Actinomyces and flavobacterium peritonitis in a patient on CAPD. Perit Dial Int. 1986;6:156.
Kodali U, Mallavarapu R, Goldberg MJ. Abdominal actinomycosis presenting as lower gastrointestinal bleeding. Endoscopy. 2003;35:451-453.
Siu YP, Tong MK, Lee MK, Leung KT, Kwan TH. Exit-site infection caused by Actinomyces odontolyticus in a CAPD patient. Perit Dial Int. 2004;24:602-603.
Hiremath S, Biyani M. Actinomyces peritonitis in a patient on continuous cycler peritoneal dialysis. Perit Dial Int. 2006;26:513-514.
Cirino CM, Paal E, Gibert CL. An elderly man receiving hemodialysis who had diarrhea, weight loss, and liver mass. Clin Infect Dis. 2007;44:269-271. 306-9.
Uehara Y, Takahashi T, Yagoshi M, et al. Liver abscess of Actinomyces israelii in a hemodialysis patient: Case report and review of the literature. Intern Med. 2010;49:2017-2020.
Diaz R, Bajo MA, Del Peso G, Garcia-Perea A, Sanchez-Villanueva R, Selgas R. Actinomyces peritonitis: Removal of the peritoneal catheter unnecessary for resolution. NDT Plus. 2010;3:296-297.
Pourmand MRDS, Hadjati M, Kosari F, Pourmand G. Renal actinomycosis in presence of renal stones in a patient with end stage renal disease. J Med Bacteriol. 2012;1:62-65.
Lin C-DT, Huai-Ching T, Wang C-C, et al. Renal actinomycosis-an unusual cause of a renal abscess. Urol Sci. 2012;23:129-132.
Abed T, Ahmed J, O'Shea N, Payne S, Watters GW. Primary laryngeal actinomycosis in an immunosuppressed woman: a case report. Ear Nose Throat J. 2013;92:301-303.
Nagaraju SP, Kirpalani DA, Bhabhe AS, Prasad R, Shah H, Kirpalani AL. Esophageal actinomycosis in a patient with end-stage renal disease. Hemodial Int. 2014;18:544-546.
Varughese S, Bargman J. Actinomyces neuii PD peritonitis-resolution of infection without catheter removal. Perit Dial Int. 2014;34:815-816.
El Kossi MMDS, Agwuh K, Milupi M. Peritoneal dialysis exit-site leak complicated by peritoneal dialysis-related peritonitis due to Actinomyces neuii. JMM Case Rep. 2015;2:1-3.
Ozkan A, Topkara A, Ozcan RH. Facial actinomycosis mimicking a cutaneous tumor. Wounds. 2017;29:10-13.
Coulon A, Kamat R, Jaikishen A, Naljayan M. Actinomyces peritonitis: a unique therapy. Am J Med Sci. 2017;354:521-522.
Yang WT, Grant M. Actinomyces neuii: A case report of a rare cause of acute infective endocarditis and literature review. BMC Infect Dis. 2019;19:511.
Yamada Y, Kinoshita C, Nakagawa H. Lumbar vertebral osteomyelitis and psoas abscess caused by Actinomyces israelii after an operation under general anesthesia in a patient with end-stage renal disease: a case report. J Med Case Rep. 2019;13:351.
Barron-Reyes GN, Curiel-Valdes JD, Beristain-Hernandez JL. Esophageal actinomycosis in an end-stage renal disease patient: What can we expect to see? Am J Gastroenterol. 2020;115:318.
Valour F, Senechal A, Dupieux C, et al. Actinomycosis: Etiology, clinical features, diagnosis, treatment, and management. Infect Drug Resist. 2014;7:183-197.

Auteurs

Leon Hsueh (L)

Department of Medicine, Veterans Affairs Medical Center, Providence, RI, USA.
Warren Alpert Medical School of Brown University, Providence, RI, USA.

Sumanth Kacharam (S)

Warren Alpert Medical School of Brown University, Providence, RI, USA.
Division of Nephrology, Medical Service, Veterans Affairs Medical Center, Providence, Rhode Island, USA.

Ankur D Shah (AD)

Warren Alpert Medical School of Brown University, Providence, RI, USA.
Division of Nephrology, Medical Service, Veterans Affairs Medical Center, Providence, Rhode Island, USA.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH