Mobile Delivery of the Diabetes Prevention Program in People With Prediabetes: Randomized Controlled Trial.
body weight
mHealth
mobile app
mobile phone
prediabetes
randomized controlled trial
Journal
JMIR mHealth and uHealth
ISSN: 2291-5222
Titre abrégé: JMIR Mhealth Uhealth
Pays: Canada
ID NLM: 101624439
Informations de publication
Date de publication:
08 07 2020
08 07 2020
Historique:
received:
17
01
2020
accepted:
15
04
2020
revised:
03
04
2020
pubmed:
28
5
2020
medline:
7
4
2021
entrez:
28
5
2020
Statut:
epublish
Résumé
The Centers for Disease Control and Prevention (CDC) diabetes prevention program (DPP) has formed the foundation for Type 2 Diabetes Mellitus (T2DM) prevention efforts and lifestyle change modifications in multiple care settings. To our knowledge, no randomized controlled trial has verified the efficacy of a fully mobile version of CDC's diabetes prevention program (DPP). This study aimed to investigate the long-term weight loss and glycemic efficacy of a mobile-delivered DPP compared with a control group receiving usual medical care. Adults with prediabetes (N=202) were recruited from a clinic and randomized to either a mobile-delivered, coach-guided DPP (Noom) or a control group that received regular medical care including a paper-based DPP curriculum and no formal intervention. The intervention group learned how to use the Noom program, how to interact with their coach, and the importance of maintaining motivation. They had access to an interactive coach-to-participant interface and group messaging, daily challenges for behavior change, DPP-based education articles, food logging, and automated feedback. Primary outcomes included changes in weight and hemoglobin A A total of 202 participants were recruited and randomized into the intervention (n=101) or control group (n=99). In the intention-to-treat (ITT) analyses, changes in the participants' weight and BMI were significantly different at 6 months between the intervention and control groups, but there was no difference in HbA This novel mobile-delivered DPP achieved significant weight loss reductions for up to 1 year compared with usual care. This type of intervention reduces the risk of overt diabetes without the added barriers of in-person interventions. ClinicalTrials.gov NCT03865342; https://clinicaltrials.gov/ct2/show/NCT03865342.
Sections du résumé
BACKGROUND
The Centers for Disease Control and Prevention (CDC) diabetes prevention program (DPP) has formed the foundation for Type 2 Diabetes Mellitus (T2DM) prevention efforts and lifestyle change modifications in multiple care settings. To our knowledge, no randomized controlled trial has verified the efficacy of a fully mobile version of CDC's diabetes prevention program (DPP).
OBJECTIVE
This study aimed to investigate the long-term weight loss and glycemic efficacy of a mobile-delivered DPP compared with a control group receiving usual medical care.
METHODS
Adults with prediabetes (N=202) were recruited from a clinic and randomized to either a mobile-delivered, coach-guided DPP (Noom) or a control group that received regular medical care including a paper-based DPP curriculum and no formal intervention. The intervention group learned how to use the Noom program, how to interact with their coach, and the importance of maintaining motivation. They had access to an interactive coach-to-participant interface and group messaging, daily challenges for behavior change, DPP-based education articles, food logging, and automated feedback. Primary outcomes included changes in weight and hemoglobin A
RESULTS
A total of 202 participants were recruited and randomized into the intervention (n=101) or control group (n=99). In the intention-to-treat (ITT) analyses, changes in the participants' weight and BMI were significantly different at 6 months between the intervention and control groups, but there was no difference in HbA
CONCLUSIONS
This novel mobile-delivered DPP achieved significant weight loss reductions for up to 1 year compared with usual care. This type of intervention reduces the risk of overt diabetes without the added barriers of in-person interventions.
TRIAL REGISTRATION
ClinicalTrials.gov NCT03865342; https://clinicaltrials.gov/ct2/show/NCT03865342.
Identifiants
pubmed: 32459631
pii: v8i7e17842
doi: 10.2196/17842
pmc: PMC7381044
doi:
Substances chimiques
Blood Glucose
0
Glycated Hemoglobin A
0
Banques de données
ClinicalTrials.gov
['NCT03865342']
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
e17842Informations de copyright
©Tatiana Toro-Ramos, Andreas Michaelides, Maria Anton, Zulekha Karim, Leah Kang-Oh, Charalambos Argyrou, Elisavet Loukaidou, Marina M Charitou, Wilson Sze, Joshua D Miller. Originally published in JMIR mHealth and uHealth (http://mhealth.jmir.org), 08.07.2020.
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