A Rare Cause of Refractory Chronic Diarrhea and Cachexia: A Case Report.
Neuroendocrine tumor
Secretory diarrhea
Somatostatin analogue
Tunisia
Vipoma
Journal
Iranian journal of public health
ISSN: 2251-6085
Titre abrégé: Iran J Public Health
Pays: Iran
ID NLM: 7505531
Informations de publication
Date de publication:
Feb 2020
Feb 2020
Historique:
entrez:
29
5
2020
pubmed:
29
5
2020
medline:
29
5
2020
Statut:
ppublish
Résumé
VIPoma is an unusual neuroendocrine neoplasm that autonomously secretes VIP. It is associated with secretory diarrhea and electrolyte disturbances. Herein we report a case of a male patient, who was hospitalized in the Department of Endocrinology in Hedi Chaker Hospital, Sfax, Tunisia. He presented VIPoma syndrome, with hepatic metastases at diagnosis. He had a history of chronic, watery diarrhea. He was dehydrated with many electrolytic disorders as hypokalemia, hyponatremia and metabolic acidosis. Abdominal CT scan showed a heterogeneous mass in the pancreatic head with multiple hepatic lesions. A high VIP hormone level was found. Histological study of a liver biopsy revealed hepatic metastases of neuroendocrine carcinoma. The patient received analogues of somatostatin and systemic chemotherapy, with a transient symptomatic relief. Sadly the patient was lost to follow-up.
Types de publication
Case Reports
Langues
eng
Pagination
386-388Informations de copyright
Copyright© Iranian Public Health Association & Tehran University of Medical Sciences.
Déclaration de conflit d'intérêts
Conflict of interests The authors declare that there is no conflict of interests.
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