Universal and Serial Laboratory Testing for SARS-CoV-2 at a Long-Term Care Skilled Nursing Facility for Veterans - Los Angeles, California, 2020.
Aged
Aged, 80 and over
Betacoronavirus
/ isolation & purification
COVID-19
COVID-19 Testing
Clinical Laboratory Techniques
/ methods
Coronavirus Infections
/ diagnosis
Disease Outbreaks
/ prevention & control
Female
Humans
Long-Term Care
Los Angeles
/ epidemiology
Male
Pandemics
/ prevention & control
Pneumonia, Viral
/ diagnosis
Reverse Transcriptase Polymerase Chain Reaction
SARS-CoV-2
Skilled Nursing Facilities
Veterans
/ statistics & numerical data
Veterans Health Services
Journal
MMWR. Morbidity and mortality weekly report
ISSN: 1545-861X
Titre abrégé: MMWR Morb Mortal Wkly Rep
Pays: United States
ID NLM: 7802429
Informations de publication
Date de publication:
29 May 2020
29 May 2020
Historique:
entrez:
29
5
2020
pubmed:
29
5
2020
medline:
30
5
2020
Statut:
epublish
Résumé
On March 28, 2020, two residents of a long-term care skilled nursing facility (SNF) at the Veterans Affairs Greater Los Angeles Healthcare System (VAGLAHS) had positive test results for SARS-CoV-2, the cause of coronavirus disease 2019 (COVID-19), by reverse transcription-polymerase chain reaction (RT-PCR) testing of nasopharyngeal specimens collected on March 26 and March 27. During March 29-April 23, all SNF residents, regardless of symptoms, underwent serial (approximately weekly) nasopharyngeal SARS-CoV-2 RT-PCR testing, and positive results were communicated to the county health department. All SNF clinical and nonclinical staff members were also screened for SARS-CoV-2 by RT-PCR during March 29-April 10. Nineteen of 99 (19%) residents and eight of 136 (6%) staff members had positive test results for SARS-CoV-2 during March 28-April 10; no further resident cases were identified on subsequent testing on April 13, April 22, and April 23. Fourteen of the 19 residents with COVID-19 were asymptomatic at the time of testing. Among these residents, eight developed symptoms 1-5 days after specimen collection and were later classified as presymptomatic; one of these patients died. This report describes an outbreak of COVID-19 in an SNF, with case identification accomplished by implementing several rounds of RT-PCR testing, permitting rapid isolation of both symptomatic and asymptomatic residents with COVID-19. The outbreak was successfully contained following implementation of this strategy.
Identifiants
pubmed: 32463809
doi: 10.15585/mmwr.mm6921e1
pmc: PMC7269604
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
651-655Déclaration de conflit d'intérêts
All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. No potential conflicts of interest were disclosed.
Références
MMWR Morb Mortal Wkly Rep. 2020 Mar 27;69(12):339-342
pubmed: 32214083
MMWR Morb Mortal Wkly Rep. 2020 May 01;69(17):523-526
pubmed: 32352954
N Engl J Med. 2020 Mar 19;382(12):1177-1179
pubmed: 32074444
MMWR Morb Mortal Wkly Rep. 2020 Apr 03;69(13):377-381
pubmed: 32240128
Nat Med. 2020 May;26(5):672-675
pubmed: 32296168