Highlights of the 12th International Bordetella Symposium.

Bordetella Bordetella genomics pertussis epidemiology pertussis vaccines whooping cough

Journal

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
ISSN: 1537-6591
Titre abrégé: Clin Infect Dis
Pays: United States
ID NLM: 9203213

Informations de publication

Date de publication:
03 12 2020
Historique:
received: 12 03 2020
accepted: 22 05 2020
pubmed: 29 5 2020
medline: 28 4 2021
entrez: 29 5 2020
Statut: ppublish

Résumé

To commemorate the 100th anniversary of the Nobel prize being awarded to Jules Bordet, the discoverer of Bordetella pertussis, the 12th International Bordetella Symposium was held from 9 to 12 April 2019 at the Université Libre de Bruxelles, where Jules Bordet studied and was Professor of Microbiology. The symposium attracted more than 300 Bordetella experts from 34 countries. They discussed the latest epidemiologic data and clinical aspects of pertussis, Bordetella biology and pathogenesis, immunology and vaccine development, and genomics and evolution. Advanced technological and methodological tools provided novel insights into the genomic diversity of Bordetella and a better understanding of pertussis disease and vaccine performance. New molecular approaches revealed previously unrecognized complexity of virulence gene regulation. Innovative insights into the immune responses to infection by Bordetella resulted in the development of new vaccine candidates. Such discoveries will aid in the design of more effective approaches to control pertussis and other Bordetella-related diseases.

Identifiants

pubmed: 32463883
pii: 5848261
doi: 10.1093/cid/ciaa651
pmc: PMC7713684
doi:

Substances chimiques

Pertussis Vaccine 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

2521-2526

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI137155
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI141372
Pays : United States
Organisme : NIAID NIH HHS
ID : R13 AI145245
Pays : United States
Organisme : FDA HHS
ID : R13 FD006613
Pays : United States

Informations de copyright

© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

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Auteurs

Camille Locht (C)

Université Lille, Centre National de la Recherche Scientifique, Inserm, Centre Hospitalier Universitaire Lille, Institut Pasteur de Lille, U1019, Unité Mixte de Recherche 8204, Center for Infection and Immunity of Lille, Lille, France.

Nicholas H Carbonetti (NH)

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.

James D Cherry (JD)

David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.

F Heath Damron (FH)

Department of Microbiology, Immunology and Cell Biology, West Virginia University, Morgantown, West Virginia, USA.
Vaccine Development Center at West Virginia University Health Science Center, West Virginia University, Morgantown, West Virginia, USA.

Kathryn M Edwards (KM)

Division of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Rachel Fernandez (R)

Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada.

Eric T Harvill (ET)

Department of Infectious Diseases, College of Veterinary Sciences, University of Georgia, Athens, Georgia, USA.

Daniela Hozbor (D)

Laboratorio VacSal, Instituto de Biotecnología y Biología Molecular, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Consejo Nacional de Investigaciones Cientificas y Técnicas, La Plata, Argentina.

Kingston H G Mills (KHG)

School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.

Maria Eugenia Rodriguez (ME)

Centro de Investigacion y Desarrollo en Fermentaciones Industriales, Consejo Nacional de Investigaciones Cientificas y Técnicas, La Plata, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina.

Françoise Mascart (F)

Laboratory of Vaccinology and Mucosal Immunity, Université Libre de Bruxelles, Brussels, Belgium.

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