A

Antimalarial diterpenes Asteraceae Metabolomic Multivariate data analysis NMR Psiadia arguta

Journal

Phytochemistry
ISSN: 1873-3700
Titre abrégé: Phytochemistry
Pays: England
ID NLM: 0151434

Informations de publication

Date de publication:
Aug 2020
Historique:
received: 16 12 2019
revised: 11 05 2020
accepted: 11 05 2020
pubmed: 29 5 2020
medline: 4 8 2020
entrez: 29 5 2020
Statut: ppublish

Résumé

Psiadia arguta (Asteraceae) is endemic to the island of Mauritius in the Indian Ocean. The species is traditionally used to treat various ailments, such as its use as an expectorant or for the treatment of bronchitis and asthma. Preliminary biological screenings have displayed the antimalarial (Plasmodium falciparum) and anticancer (HeLa human cell line) potential of P. arguta leaves. The phytochemical investigation of this plant has led to the isolation and characterization of sixteen compounds including five antiplasmodial molecules. The accumulation of the antiplasmodial compounds during the growth of the plant was studied by a

Identifiants

pubmed: 32464510
pii: S0031-9422(19)31212-9
doi: 10.1016/j.phytochem.2020.112401
pii:
doi:

Substances chimiques

Antimalarials 0
Plant Extracts 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

112401

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Keshika Mahadeo (K)

Laboratoire de Chimie des Substances Naturelles et des Sciences des Aliments, Faculté des Sciences et Technologies, Université de La Réunion, 15 Avenue René Cassin, CS 92 003, 97 744, St Denis Cedex 9, La Réunion, France; UMR Qualisud, Université de La Réunion, 15 Avenue René Cassin, CS 92 003, 97 744, St Denis Cedex 9, La Réunion, France.

Isabelle Grondin (I)

Laboratoire de Chimie des Substances Naturelles et des Sciences des Aliments, Faculté des Sciences et Technologies, Université de La Réunion, 15 Avenue René Cassin, CS 92 003, 97 744, St Denis Cedex 9, La Réunion, France.

Gaëtan Herbette (G)

Aix-Marseille Univ, CNRS, Centrale Marseille, FSCM, Spectropole, Campus de St Jérôme-Service 511, 13397, Marseille, France.

Tony L Palama (TL)

Université Sorbonne Paris Nord, Laboratoire de Chimie, Structures, Propriétés de Biomatériaux et d'Agents Thérapeutiques, CSPBAT, CNRS, UMR 7244, F, 93430, Villetaneuse, France.

Nadia Bouchemal (N)

Université Sorbonne Paris Nord, Laboratoire de Chimie, Structures, Propriétés de Biomatériaux et d'Agents Thérapeutiques, CSPBAT, CNRS, UMR 7244, F, 93430, Villetaneuse, France.

Joyce Soulange (J)

Department of Agriculture and Food Science, Faculty of Agriculture, The University of Mauritius, Mauritius.

Sabina Jhaumeer Laulloo (SJ)

Department of Chemistry, Faculty of Science, The University of Mauritius, Mauritius.

Joelle Sadeyen (J)

UMR Peuplement Végétaux et Bio-agresseurs en Milieu Tropical, Université de La Réunion, 15 Avenue René Cassin, CS 92 003, 97 744 St Denis Cedex 9, La Réunion, France.

Laurence Humeau (L)

UMR Peuplement Végétaux et Bio-agresseurs en Milieu Tropical, Université de La Réunion, 15 Avenue René Cassin, CS 92 003, 97 744 St Denis Cedex 9, La Réunion, France.

Michel Frederich (M)

Université de Liège, Département de Pharmacie, Centre Interfacultaire de Recherche sur le Médicament (CIRM), Laboratoire de Pharmacognosie, Campus du Sart-Tilman, Quartier Hôpital, Avenue Hippocrate, 15 B36 4000 Liège, Belgium.

Anne Gauvin-Bialecki (A)

Laboratoire de Chimie des Substances Naturelles et des Sciences des Aliments, Faculté des Sciences et Technologies, Université de La Réunion, 15 Avenue René Cassin, CS 92 003, 97 744, St Denis Cedex 9, La Réunion, France.

Hippolyte Kodja (H)

UMR Qualisud, Université de La Réunion, 15 Avenue René Cassin, CS 92 003, 97 744, St Denis Cedex 9, La Réunion, France. Electronic address: hippolyte.kodja@univ-reunion.fr.

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Classifications MeSH