Animals
Bone Morphogenetic Protein 4
/ metabolism
Cleft Lip
/ embryology
Female
Gene Expression Regulation, Developmental
Genome
Homeodomain Proteins
/ metabolism
Humans
Hypoxia
/ embryology
Lip
/ embryology
MSX1 Transcription Factor
/ deficiency
Mesoderm
/ embryology
Mice, Inbred C57BL
Morphogenesis
/ genetics
Mutation
/ genetics
Nose
/ embryology
Oxygen
/ metabolism
PAX9 Transcription Factor
/ metabolism
Phenytoin
Respiration
Up-Regulation
/ genetics
Cleft lip and palate
Hypoxia
Morphogenetic regulation
Msx1
Pax9
Journal
Development (Cambridge, England)
ISSN: 1477-9129
Titre abrégé: Development
Pays: England
ID NLM: 8701744
Informations de publication
Date de publication:
24 06 2020
24 06 2020
Historique:
received:
17
02
2020
accepted:
16
05
2020
pubmed:
30
5
2020
medline:
29
12
2020
entrez:
30
5
2020
Statut:
epublish
Résumé
Nonsyndromic clefts of the lip and palate are common birth defects resulting from gene-gene and gene-environment interactions. Mutations in human
Identifiants
pubmed: 32467233
pii: dev.189175
doi: 10.1242/dev.189175
pii:
doi:
Substances chimiques
Bone Morphogenetic Protein 4
0
Homeodomain Proteins
0
MSX1 Transcription Factor
0
MSX2 protein
0
PAX9 Transcription Factor
0
Phenytoin
6158TKW0C5
Oxygen
S88TT14065
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Medical Research Council
ID : MR/R006237/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : G0400679
Pays : United Kingdom
Informations de copyright
© 2020. Published by The Company of Biologists Ltd.
Déclaration de conflit d'intérêts
Competing interestsThe authors declare no competing or financial interests.